Literature DB >> 1751622

Fatty acid levels in the brains of schizophrenics and normal controls.

D F Horrobin1, M S Manku, H Hillman, A Iain, M Glen.   

Abstract

Essential fatty acids are important constituents of the brain. There is evidence that levels in blood of certain essential fatty acids and their eicosanoid derivatives may be abnormal. We now report that in the frontal cortex of schizophrenic patients there are significant differences from normal in the fatty acid composition of phosphatidylethanolamine. These differences from normal were not found in the cerebellar cortex.

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Year:  1991        PMID： 1751622     DOI： 10.1016/0006-3223(91)90235-e

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN： 0006-3223            Impact factor:   13.382


  31 in total

1.  Investigation of postmortem brain polyunsaturated fatty acid composition in psychiatric disorders: limitations, challenges, and future directions.

Authors:  Robert K McNamara; Ronald Jandacek
Journal:  J Psychiatr Res       Date:  2010-05-26       Impact factor: 4.791

2.  Adolescent behavior and dopamine availability are uniquely sensitive to dietary omega-3 fatty acid deficiency.

Authors:  Corina O Bondi; Ameer Y Taha; Jody L Tock; Nelson K B Totah; Yewon Cheon; Gonzalo E Torres; Stanley I Rapoport; Bita Moghaddam
Journal:  Biol Psychiatry       Date:  2013-07-25       Impact factor: 13.382

3.  Fish oil and antipsychotic drug risperidone modulate oxidative stress in PC12 cell membranes through regulation of cytosolic calcium ion release and antioxidant system.

Authors:  Sevil Altinkiliç; Mustafa Naziroğlu; Abdülhadi Cihangir Uğuz; Ramazan Ozcankaya
Journal:  J Membr Biol       Date:  2010-06-24       Impact factor: 1.843

Review 4.  Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view.

Authors:  Jeffrey K Yao; Matcheri S Keshavan
Journal:  Antioxid Redox Signal       Date:  2011-04-21       Impact factor: 8.401

5.  Dietary n-6 PUFA deprivation for 15 weeks reduces arachidonic acid concentrations while increasing n-3 PUFA concentrations in organs of post-weaning male rats.

Authors:  Miki Igarashi; Fei Gao; Hyung-Wook Kim; Kaizong Ma; Jane M Bell; Stanley I Rapoport
Journal:  Biochim Biophys Acta       Date:  2008-11-27

6.  Abnormal fatty acid pattern in the superior temporal gyrus distinguishes bipolar disorder from major depression and schizophrenia and resembles multiple sclerosis.

Authors:  Robert K McNamara; Therese Rider; Ronald Jandacek; Patrick Tso
Journal:  Psychiatry Res       Date:  2014-01-02       Impact factor: 3.222

7.  Chronic risperidone treatment preferentially increases rat erythrocyte and prefrontal cortex omega-3 fatty acid composition: evidence for augmented biosynthesis.

Authors:  Robert K McNamara; Jessica A Able; Ronald Jandacek; Therese Rider; Patrick Tso
Journal:  Schizophr Res       Date:  2008-11-07       Impact factor: 4.939

8.  Altered fatty acid concentrations in prefrontal cortex of schizophrenic patients.

Authors:  Ameer Y Taha; Yewon Cheon; Kaizong Ma; Stanley I Rapoport; Jagadeesh S Rao
Journal:  J Psychiatr Res       Date:  2013-02-18       Impact factor: 4.791

9.  Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: no changes in docosahexaenoic acid species.

Authors:  Kei Hamazaki; Kwang H Choi; Hee-Yong Kim
Journal:  J Psychiatr Res       Date:  2010-01-06       Impact factor: 4.791

Review 10.  Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: a review of the evidence and putative mechanisms.

Authors:  Ryan J Van Lieshout; Lakshmi P Voruganti
Journal:  J Psychiatry Neurosci       Date:  2008-09       Impact factor: 6.186
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