BACKGROUND: In this prospective, randomized, double-blind study, we evaluated whether a very low dose of spinal bupivacaine could be sufficient for safe performance of short perianal surgery. METHODS:Eighty patients were randomly assigned to receive hyperbaric bupivacaine doses of either 1.5 mg (n = 40) or 6.0 mg (n = 40). RESULTS: The lower dose produced satisfactory anesthesia with a more limited block (median S4; P < 0.01), earlier time to ambulation (98 vs 147 min; P < 0.01), and hospital discharge (126 vs 249 min; P < 0.01), compared with the higher spinal dose. CONCLUSIONS: The use of 1.5 mg spinal bupivacaine can be successful for short perianal surgery.
RCT Entities:
BACKGROUND: In this prospective, randomized, double-blind study, we evaluated whether a very low dose of spinal bupivacaine could be sufficient for safe performance of short perianal surgery. METHODS: Eighty patients were randomly assigned to receive hyperbaric bupivacaine doses of either 1.5 mg (n = 40) or 6.0 mg (n = 40). RESULTS: The lower dose produced satisfactory anesthesia with a more limited block (median S4; P < 0.01), earlier time to ambulation (98 vs 147 min; P < 0.01), and hospital discharge (126 vs 249 min; P < 0.01), compared with the higher spinal dose. CONCLUSIONS: The use of 1.5 mg spinal bupivacaine can be successful for short perianal surgery.
Authors: Marc D Schmittner; Tom Terboven; Michael Dluzak; Andrea Janke; Marc E Limmer; Christel Weiss; Dieter G Bussen; Marc A Burmeister; Grietje C Beck Journal: Int J Colorectal Dis Date: 2010-02-11 Impact factor: 2.571
Authors: Marc D Schmittner; Nicole Urban; Andrea Janke; Christel Weiss; Dieter G Bussen; Marc A Burmeister; Grietje C Beck Journal: Int J Colorectal Dis Date: 2010-07-22 Impact factor: 2.571
Authors: Marc D Schmittner; Andrea Janke; Christel Weiss; Grietje C Beck; Dieter G Bussen Journal: Int J Colorectal Dis Date: 2009-03-13 Impact factor: 2.571