Andrea M Barsevick1. 1. Nursing Research, Fax Chase Cancer Center, Philadelphia, PA, USA. Andrea.Barsevick@fccc.edu
Abstract
OBJECTIVES: To define the concept of a symptom cluster, evaluate the evidence base in support of it, and address research and clinical implications. DATA SOURCES: Review of descriptive research that examined fatigue, insomnia, pain, or depression in relation to other symptoms. CONCLUSION: More investigation is needed. There is evidence of overlapping variance indicative of a relationship between or among symptoms. Few studies have addressed the outcomes of symptom clusters. There is limited evidence of symptom concurrence or a common biological pathway for clustered symptoms. IMPLICATIONS FOR NURSING PRACTICE: Consideration should be given to assessment and management of fatigue, insomnia, pain, and depression as potential "sentinel symptoms" that could affect patient outcomes.
OBJECTIVES: To define the concept of a symptom cluster, evaluate the evidence base in support of it, and address research and clinical implications. DATA SOURCES: Review of descriptive research that examined fatigue, insomnia, pain, or depression in relation to other symptoms. CONCLUSION: More investigation is needed. There is evidence of overlapping variance indicative of a relationship between or among symptoms. Few studies have addressed the outcomes of symptom clusters. There is limited evidence of symptom concurrence or a common biological pathway for clustered symptoms. IMPLICATIONS FOR NURSING PRACTICE: Consideration should be given to assessment and management of fatigue, insomnia, pain, and depression as potential "sentinel symptoms" that could affect patient outcomes.
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