Literature DB >> 17512189

Oesophageal cancer in The Netherlands: increasing incidence and mortality but improving survival.

Lucia M A Crane1, Michael Schaapveld, Otto Visser, Marieke W J Louwman, John T M Plukker, Gooitzen M van Dam.   

Abstract

AIM: Oesophageal cancer is highly lethal with a 5-year relative survival of 10-15%. An increasing incidence has been reported for several parts of the Western world. We studied time trends in incidence, mortality and survival for oesophageal cancer in the Netherlands during 1989-2003.
METHODS: Data on incidence and survival were obtained from the Netherlands Cancer Registry and mortality data from Statistics Netherlands.
RESULTS: The age standardised incidence increased by 3.4% (p<0.001) and 1.9% (p=0.003) per year for males and females, respectively. This increase was almost exclusively caused by oesophageal adenocarcinomas. Age standardised mortality increased 2.5% (p<0.001) per year among males and 1.7% (p=0.002) per year among females. Relative survival improved significantly from 8.1% in 1989-1993 to 12.6% in 1999-2003 (p<0.001). Adjusted for age, stage, tumour location and surgery, the excess risk of death decreased by 22%.
CONCLUSION: Oesophageal carcinoma incidence is rising in the Netherlands. Mortality increased at a slightly lower pace due to improving survival.

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Year:  2007        PMID: 17512189     DOI: 10.1016/j.ejca.2007.03.024

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


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