Literature DB >> 17508788

"All possible steps" approach to the accelerated use of Gillespie's algorithm.

Azi Lipshtat1.   

Abstract

Many physical and biological processes are stochastic in nature. Computational models and simulations of such processes are a mathematical and computational challenge. The basic stochastic simulation algorithm was published by Gillespie about three decades ago [J. Phys. Chem. 81, 2340 (1977)]. Since then, intensive work has been done to make the algorithm more efficient in terms of running time. All accelerated versions of the algorithm are aimed at minimizing the running time required to produce a stochastic trajectory in state space. In these simulations, a necessary condition for reliable statistics is averaging over a large number of simulations. In this study the author presents a new accelerating approach which does not alter the stochastic algorithm, but reduces the number of required runs. By analysis of collected data the author demonstrates high precision levels with fewer simulations. Moreover, the suggested approach provides a good estimation of statistical error, which may serve as a tool for determining the number of required runs.

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Year:  2007        PMID: 17508788     DOI: 10.1063/1.2730507

Source DB:  PubMed          Journal:  J Chem Phys        ISSN: 0021-9606            Impact factor:   3.488


  1 in total

1.  An efficient method for computing steady state solutions with Gillespie's direct method.

Authors:  S Mauch; M Stalzer
Journal:  J Chem Phys       Date:  2010-10-14       Impact factor: 3.488

  1 in total

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