Literature DB >> 17508625

Stannous fluoride/sodium hexametaphosphate dentifrice increases dentin resistance to tubule exposure in vitro.

Donald J White1, Michelle A Lawless, Ayowumi Fatade, Arif Baig, Roxana von Koppenfels, Heinz Duschner, Hermann Götz.   

Abstract

OBJECTIVE: The purpose of this study was to compare the reactivity of three dentifrice formulations on smear layer-covered root dentin surfaces, and the effects of the formulation treatments on resistance to acid softening and dentinal tubuli disclosure.
METHODOLOGY: Commercial dentifrices, including Crest Cavity Protection Regular, Colgate Total, and a new dentifrice comprised of stannous fluoride/sodium hexametaphosphate (SnF2/HMP: Crest Pro-Health), were cycled through a pre-treatment period on smear layer-covered dentin surfaces, including intermittent soaking in dentifrice slurries and whole human saliva immersion. Following pre-treatments, the cycling treatments were modified to include dietary acid exposure, including soaks in an acidic soft drink. Vickers surface microhardness, variable pressure scanning electron microscopy (VP-SEM), and confocal laser scanning microscopy in reflection mode (CLSM) were used to characterize dentin reactivity and smear layer protection.
RESULTS: CLSM and SEM analyses showed that specimens treated with SnF2/HMP appeared to resist acid solubilization, evidenced by the absence of disclosed dentinal tubuli. The histo-tomographic observations in this study were in agreement with the hardness measurements. The superior surface protection of dentin with SnF2/HMP would suggest potential benefits in ameliorating dentinal hypersensitivity in the clinical situation.
CONCLUSION: A stannous fluoride/sodium hexametaphosphate dentifrice prevents dietary acid softening and tubule exposure of smear layer dentin surfaces.

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Year:  2007        PMID: 17508625

Source DB:  PubMed          Journal:  J Clin Dent        ISSN: 0895-8831


  7 in total

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2.  Comparative Study of Technologies for Tubule Occlusion and Treatment of Dentin Hypersensitivity.

Authors:  Camilla Berg; Erik Unosson; Håkan Engqvist; Wei Xia
Journal:  J Funct Biomater       Date:  2021-04-27

3.  A randomised in situ trial, measuring the anti-erosive properties of a stannous-containing sodium fluoride dentifrice compared with a sodium fluoride/potassium nitrate dentifrice.

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4.  Erosion protection benefits of stabilized SnF2 dentifrice versus an arginine-sodium monofluorophosphate dentifrice: results from in vitro and in situ clinical studies.

Authors:  N X West; T He; E L Macdonald; J Seong; N Hellin; M L Barker; S L Eversole
Journal:  Clin Oral Investig       Date:  2016-08-01       Impact factor: 3.573

Review 5.  Formulations of desensitizing toothpastes for dentin hypersensitivity: a scoping review.

Authors:  Carolina Castro Martins; John Joseph Riva; Ramon Targino Firmino; Holger Jens Schünemann
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6.  Effects on dentin treated with eluted multi-mineral varnish in vitro.

Authors:  Robert L Karlinsey; Allen C Mackey; Craig S Schwandt
Journal:  Open Dent J       Date:  2012-10-05

7.  Protective effects of SnF2 - Part I. Mineral solubilisation studies on powdered apatite.

Authors:  Arif A Baig; Robert V Faller; Janet Yan; Nelson Ji; Michelle Lawless; Sandra L Eversole
Journal:  Int Dent J       Date:  2014-03       Impact factor: 2.607

  7 in total

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