Literature DB >> 17507152

The use of local anesthesia with N-DO injector (Physion) for transurethral resection (TUR) of bladder tumors and bladder mapping: preliminary results and cost-effectiveness analysis.

Maurizio A Brausi1, Giorgio Verrini, Giuseppe De Luca, Massimo Viola, Gian Luca Simonini, Giancarlo Peracchia, Mirko Gavioli.   

Abstract

OBJECTIVE: We evaluated feasibility of TUR of Ta-T1 TCC of the bladder or bladder mapping under local anesthesia using a Physion endoinjector to see if correct tumor staging was possible, to check patient tolerability, and to analyze cost-effectiveness.
METHODS: Thirty patients with bladder tumors and 10 patients with hematuria and/or doubtful cytologies were treated in a day hospital setting. TUR or biopsies were performed after injecting lidocaine into the outer area of the lesion in the bladder at 2-3 sites under the mucosa. A single injection per biopsy site was necessary for bladder mapping. We evaluated tolerability using the VAS questionnaire. Cost analysis considered length of hospital stay, number of anesthesiological procedures, and complications.
RESULTS: The stage and grade after TUR were 19 TaG1-2, 10 T1G2, and 1 papillary hyperplasia. After bladder mapping, 5 patients had CIS and 5 had inflammation. Sixty percent of patients had no or mild pain, 30% moderate pain requiring light sedation or analgesia, and 10% severe pain requiring spinal or general anesthesia. The mean hospital stay was 9h. Four of 40 patients complained of macroscopic hematuria; one was readmitted to the ward. This procedure saved 1097.07 euros per case and 36 anesthesiological procedures were avoided.
CONCLUSIONS: This is a simple, safe, cost-effective technique, allowing TUR of bladder tumors and bladder mapping in 60% of patients and, with light sedation or analgesia, in 90% of patients, with a low complication rate. Tumor staging was correct in 90% of cases. The mean hospital stay was 9h.

Entities:  

Mesh:

Year:  2007        PMID: 17507152     DOI: 10.1016/j.eururo.2007.04.086

Source DB:  PubMed          Journal:  Eur Urol        ISSN: 0302-2838            Impact factor:   20.096


  5 in total

1.  Levobupivacaine intravesical injection for superficial bladder tumor resection--possible, effective, and durable. Preliminary clinical data.

Authors:  K G Stravodimos; D Mitropoulos; A Salvari; A Lampadariou; T Kapetanakis; A Zervas
Journal:  Int Urol Nephrol       Date:  2007-11-13       Impact factor: 2.370

Review 2.  The health economics of bladder cancer: an updated review of the published literature.

Authors:  Christina Yeung; Tuan Dinh; Joseph Lee
Journal:  Pharmacoeconomics       Date:  2014-11       Impact factor: 4.981

3.  Procedure-related pain among adult patients with hematologic malignancies.

Authors:  Y Lidén; O Landgren; S Arnér; K-F Sjölund; E Johansson
Journal:  Acta Anaesthesiol Scand       Date:  2009-03       Impact factor: 2.105

4.  Spinal versus General Anaesthesia in Postoperative Pain Management during Transurethral Procedures.

Authors:  Stavros I Tyritzis; Konstantinos G Stravodimos; Ioanna Vasileiou; Georgia Fotopoulou; Georgios Koritsiadis; Vasileios Migdalis; Anastasios Michalakis; Constantinos A Constantinides
Journal:  ISRN Urol       Date:  2011-07-12

5.  A Comparison of the Anesthetic Methods for Recurrence Rates of Bladder Cancer after Transurethral Resection of Bladder Tumors Using National Health Insurance Claims Data of South Korea.

Authors:  Sang Won Lee; Bum Sik Tae; Yoon Ji Choi; Sang Min Yoon; Yoon Sook Lee; Jae Hwan Kim; Hye Won Shin; Jae Young Park; Jae Hyun Bae
Journal:  J Clin Med       Date:  2022-02-21       Impact factor: 4.241

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.