| Literature DB >> 17504504 |
S E L Temple1, C M Almeida, K Y Cheong, R G Wunderink, G W Waterer.
Abstract
We sequenced the lymphotoxin alpha (LTA) promoter and identified LTA10G>A in strong linkage with LTA252G>A and LTA723C>A. Stimulated cells from LTA723AA: LTA252GG:LTA10AA individuals had significantly higher LTA mRNA levels than LTA723CC:LTA252AA:LTA10GG and LTA723AA:LTA252AG:LTA10GA individuals, suggesting that this diplotype may contain a functional polymorphism explaining the observed disease associations with LTA252G>A.Entities:
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Year: 2007 PMID： 17504504 DOI： 10.1111/j.1744-313X.2007.00674.x
Source DB: PubMed Journal: Int J Immunogenet ISSN： 1744-3121 Impact factor: 1.466