Literature DB >> 17503873

The evidence for chronic traumatic encephalopathy in boxing.

Paul McCrory1, Tsharni Zazryn, Peter Cameron.   

Abstract

The sport of boxing has been the source of much debate, with concerns about the neurological risks of participating having led to many calls to ban the sport. This review seeks to establish an evidence base for the development of boxing-related chronic traumatic encephalopathy (CTE) and to determine the relevance of this information to the modern day sport.The clinical features of CTE include various symptoms affecting the pyramidal and extrapyramidal systems, which manifest most often as disturbed gait and coordination, slurred speech and tremors, as well as cerebral dysfunction causing cognitive impairments and neurobehavioural disturbances. Both amateur and professional boxers are potentially at risk of developing CTE. No current epidemiological evidence exists to determine the prevalence of this condition in modern day boxing, despite 17% of professional boxers in Britain with careers in the 1930-50s having clinical evidence of CTE. As medical presence within the sport increases and with modern boxers likely to have shorter careers, a reduced exposure to repetitive head trauma, and improved treatment and understanding of the development of CTE will occur. This should lead to the incidence of CTE diminishing in boxing populations.

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Year:  2007        PMID: 17503873     DOI: 10.2165/00007256-200737060-00001

Source DB:  PubMed          Journal:  Sports Med        ISSN: 0112-1642            Impact factor:   11.928


  73 in total

1.  A 9-year controlled prospective neuropsychologic assessment of amateur boxing.

Authors:  Mark D Porter
Journal:  Clin J Sport Med       Date:  2003-11       Impact factor: 3.638

2.  The mechanisms of cerebral concussion in boxing and their consequences.

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Journal:  World Neurol       Date:  1962-05

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Journal:  Acta Neurol Scand       Date:  1990-10       Impact factor: 3.209

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Authors:  R L Heilbronner; G K Henry; M Carson-Brewer
Journal:  Am J Sports Med       Date:  1991 Jul-Aug       Impact factor: 6.202

5.  Cephalic magnetic resonance imaging of boxers. Preliminary results.

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6.  Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing.

Authors:  B D Jordan; N R Relkin; L D Ravdin; A R Jacobs; A Bennett; S Gandy
Journal:  JAMA       Date:  1997-07-09       Impact factor: 56.272

7.  Is chronic brain damage in boxing a hazard of the past?

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Journal:  Lancet       Date:  1982-11-27       Impact factor: 79.321

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Authors:  I R Casson; O Siegel; R Sham; E A Campbell; M Tarlau; A DiDomenico
Journal:  JAMA       Date:  1984-05-25       Impact factor: 56.272

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Authors:  Lisa D Ravdin; William B Barr; Barry Jordan; William E Lathan; Norman R Relkin
Journal:  Clin J Sport Med       Date:  2003-01       Impact factor: 3.638

10.  The significance of diagnostic imaging in acute and chronic brain damage in boxing. A prospective study in amateur boxing using magnetic resonance imaging (MRI).

Authors:  M Holzgraefe; W Lemme; W Funke; R Felix; R Felten
Journal:  Int J Sports Med       Date:  1992-11       Impact factor: 3.118

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  24 in total

1.  Boxing and the risk of chronic brain injury.

Authors:  Paul McCrory
Journal:  BMJ       Date:  2007-10-04

Review 2.  Amateur boxing and risk of chronic traumatic brain injury: systematic review of observational studies.

Authors:  Mike Loosemore; Charles H Knowles; Greg P Whyte
Journal:  BMJ       Date:  2007-10-04

3.  The Role of Acid Sphingomyelinase Inhibition in Repetitive Mild Traumatic Brain Injury.

Authors:  Grace M Niziolek; Richard S Hoehn; Aaron P Seitz; Peter L Jernigan; Amy T Makley; Erich Gulbins; Michael J Edwards; Michael D Goodman
Journal:  J Surg Res       Date:  2020-10-29       Impact factor: 2.192

4.  Theta burst stimulation to characterize changes in brain plasticity following mild traumatic brain injury: A proof-of-principle study.

Authors:  Sara Tremblay; Marine Vernet; Shahid Bashir; Alvaro Pascual-Leone; Hugo Théoret
Journal:  Restor Neurol Neurosci       Date:  2015       Impact factor: 2.406

Review 5.  The Biological Basis of Chronic Traumatic Encephalopathy following Blast Injury: A Literature Review.

Authors:  Matt Aldag; Regina C Armstrong; Faris Bandak; Patrick S F Bellgowan; Timothy Bentley; Sean Biggerstaff; Katrina Caravelli; Joan Cmarik; Alicia Crowder; Thomas J DeGraba; Travis A Dittmer; Richard G Ellenbogen; Colin Greene; Raj K Gupta; Ramona Hicks; Stuart Hoffman; Robert C Latta; Michael J Leggieri; Donald Marion; Robert Mazzoli; Michael McCrea; John O'Donnell; Mark Packer; James B Petro; Todd E Rasmussen; Wendy Sammons-Jackson; Richard Shoge; Victoria Tepe; Ladd A Tremaine; James Zheng
Journal:  J Neurotrauma       Date:  2017-09       Impact factor: 5.269

6.  Functionally-detected cognitive impairment in high school football players without clinically-diagnosed concussion.

Authors:  Thomas M Talavage; Eric A Nauman; Evan L Breedlove; Umit Yoruk; Anne E Dye; Katherine E Morigaki; Henry Feuer; Larry J Leverenz
Journal:  J Neurotrauma       Date:  2013-04-11       Impact factor: 5.269

Review 7.  Review: Contact sport-related chronic traumatic encephalopathy in the elderly: clinical expression and structural substrates.

Authors:  A Costanza; K Weber; S Gandy; C Bouras; P R Hof; P Giannakopoulos; A Canuto
Journal:  Neuropathol Appl Neurobiol       Date:  2011-10       Impact factor: 8.090

Review 8.  A Clinical Approach to the Diagnosis of Traumatic Encephalopathy Syndrome: A Review.

Authors:  Nicole Reams; James T Eckner; Andrea A Almeida; Andrea L Aagesen; Bruno Giordani; Hank Paulson; Matthew T Lorincz; Jeffrey S Kutcher
Journal:  JAMA Neurol       Date:  2016-06-01       Impact factor: 18.302

9.  A prospective study of physician-observed concussion during a varsity university hockey season: white matter integrity in ice hockey players. Part 3 of 4.

Authors:  Inga K Koerte; David Kaufmann; Elisabeth Hartl; Sylvain Bouix; Ofer Pasternak; Marek Kubicki; Alexander Rauscher; David K B Li; Shiroy B Dadachanji; Jack A Taunton; Lorie A Forwell; Andrew M Johnson; Paul S Echlin; Martha E Shenton
Journal:  Neurosurg Focus       Date:  2012-12       Impact factor: 4.047

10.  Effect of Weight Class on Regional Brain Volume, Cognition, and Other Neuropsychiatric Outcomes among Professional Fighters.

Authors:  Michael J C Bray; Jerry Tsai; Barry R Bryant; Bharat R Narapareddy; Lisa N Richey; Akshay Krieg; William Tobolowsky; Sahar Jahed; Guogen Shan; Charles B Bernick; Matthew E Peters
Journal:  Neurotrauma Rep       Date:  2021-03-18
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