Literature DB >> 17502414

Atorvastatin is 10-fold more active in vitro than other statins against Plasmodium falciparum.

Bruno Pradines, Marylin Torrentino-Madamet, Albin Fontaine, Maud Henry, Eric Baret, Joel Mosnier, Sébastien Briolant, Thierry Fusai, Christophe Rogier.   

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Year:  2007        PMID： 17502414      PMCID： PMC1913261          DOI： 10.1128/AAC.01330-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


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  13 in total

1.  Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase.

Authors:  A Montalvetti; J Peña-Díaz; R Hurtado; L M Ruiz-Pérez; D González-Pacanowska
Journal:  Biochem J       Date:  2000-07-01       Impact factor: 3.857

2.  Plasmodium falciparum: the lethal effects of tunicamycin and mevastatin on the parasite are not mediated by the inhibition of N-linked oligosaccharide biosynthesis.

Authors:  R S Naik; M Venkatesan; D C Gowda
Journal:  Exp Parasitol       Date:  2001-06       Impact factor: 2.011

3.  Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans.

Authors:  Jia L Song; Chris N Lyons; Scott Holleman; Brian G Oliver; Theodore C White
Journal:  Med Mycol       Date:  2003-10       Impact factor: 4.076

4.  Toxicity of statins on rat skeletal muscle mitochondria.

Authors:  P Kaufmann; M Török; A Zahno; K M Waldhauser; K Brecht; S Krähenbühl
Journal:  Cell Mol Life Sci       Date:  2006-10       Impact factor: 9.261

5.  Active isoprenoid pathway in the intra-erythrocytic stages of Plasmodium falciparum: presence of dolichols of 11 and 12 isoprene units.

Authors:  A S Couto; E A Kimura; V J Peres; M L Uhrig; A M Katzin
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

6.  Iron chelators as antimalarial agents: in vitro activity of dicatecholate against Plasmodium falciparum.

Authors:  B Pradines; J M Rolain; F Ramiandrasoa; T Fusai; J Mosnier; C Rogier; W Daries; E Baret; G Kunesch; J Le Bras; D Parzy
Journal:  J Antimicrob Chemother       Date:  2002-08       Impact factor: 5.790

7.  The effects of protein farnesyltransferase inhibitors on trypanosomatids: inhibition of protein farnesylation and cell growth.

Authors:  K Yokoyama; P Trobridge; F S Buckner; J Scholten; K D Stuart; W C Van Voorhis; M H Gelb
Journal:  Mol Biochem Parasitol       Date:  1998-07-01       Impact factor: 1.759

8.  Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.

Authors:  J A Urbina; K Lazardi; E Marchan; G Visbal; T Aguirre; M M Piras; R Piras; R A Maldonado; G Payares; W de Souza
Journal:  Antimicrob Agents Chemother       Date:  1993-03       Impact factor: 5.191

9.  Activity, pharmacological inhibition and biological regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in Trypanosoma brucei.

Authors:  I Coppens; P Bastin; T Levade; P J Courtoy
Journal:  Mol Biochem Parasitol       Date:  1995-01       Impact factor: 1.759

10.  Salmonella enterica serovar Typhimurium requires nonsterol precursors of the cholesterol biosynthetic pathway for intracellular proliferation.

Authors:  Drew M Catron; Yvonne Lange; Jayme Borensztajn; Matthew D Sylvester; Bradley D Jones; Kasturi Haldar
Journal:  Infect Immun       Date:  2004-02       Impact factor: 3.441
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  27 in total

1.  Proveblue (methylene blue) as an antimalarial agent: in vitro synergy with dihydroartemisinin and atorvastatin.

Authors:  Jérôme Dormoi; Aurélie Pascual; Sébastien Briolant; Rémy Amalvict; Serge Charras; Eric Baret; Emilie Huyghues des Etages; Michel Feraud; Bruno Pradines
Journal:  Antimicrob Agents Chemother       Date:  2012-03-05       Impact factor: 5.191

2.  Short-term pretreatment with atorvastatin attenuates left ventricular dysfunction, reduces infarct size and apoptosis in acute myocardial infarction rats.

Authors:  Tie-Long Chen; Guang-Li Zhu; Xiao-Long He; Jian-An Wang; Yu Wang; Guo-An Qi
Journal:  Int J Clin Exp Med       Date:  2014-12-15

3.  Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria.

Authors:  Robin Kobbe; Nadine Schreiber; Jürgen May; Thomas Jacobs
Journal:  Antimicrob Agents Chemother       Date:  2008-02-11       Impact factor: 5.191

4.  Statins as potential antimalarial drugs: low relative potency and lack of synergy with conventional antimalarial drugs.

Authors:  Rina P M Wong; Timothy M E Davis
Journal:  Antimicrob Agents Chemother       Date:  2009-03-02       Impact factor: 5.191

Review 5.  Diagnosis and management of the neurological complications of falciparum malaria.

Authors:  Saroj K Mishra; Charles R J C Newton
Journal:  Nat Rev Neurol       Date:  2009-04       Impact factor: 42.937

6.  Statins alone are ineffective in cerebral malaria but potentiate artesunate.

Authors:  Anne-Lise Bienvenu; Stéphane Picot
Journal:  Antimicrob Agents Chemother       Date:  2008-09-08       Impact factor: 5.191

7.  Atorvastatin as a potential antimalarial drug: in vitro synergy in combinational therapy with dihydroartemisinin.

Authors:  Hélène Savini; Jean Baptiste Souraud; Sébastien Briolant; Eric Baret; Rémy Amalvict; Christophe Rogier; Bruno Pradines
Journal:  Antimicrob Agents Chemother       Date:  2009-11-30       Impact factor: 5.191

8.  Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.

Authors:  Kovi Bessoff; Adam Sateriale; K Kyungae Lee; Christopher D Huston
Journal:  Antimicrob Agents Chemother       Date:  2013-02-04       Impact factor: 5.191

9.  Aryloxyethyl Thiocyanates Are Potent Growth Inhibitors of Trypanosoma cruzi and Toxoplasma gondii.

Authors:  María N Chao; Carolina Exeni Matiuzzi; Melissa Storey; Catherine Li; Sergio H Szajnman; Roberto Docampo; Silvia N J Moreno; Juan B Rodriguez
Journal:  ChemMedChem       Date:  2015-04-27       Impact factor: 3.466

10.  Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.

Authors:  Pablo D Elicio; María N Chao; Melina Galizzi; Catherine Li; Sergio H Szajnman; Roberto Docampo; Silvia N J Moreno; Juan B Rodriguez
Journal:  Eur J Med Chem       Date:  2013-09-18       Impact factor: 6.514
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