RATIONALE AND OBJECTIVES: To evaluate the potential usefulness of high b-value body diffusion-weighted images (DWIs) as a screening tool in the depiction of abdominal malignant tumors. MATERIALS AND METHODS: We selected 110 abdominal magnetic resonance examinations (1.5 T; 60 men; age range, 25-90 years) with and without malignant tumors (n = 37 and n = 73, respectively). Axial DWIs were obtained by single-shot spin-echo (SE) type echo planar imaging (EPI) sequence with inversion pulse (repetition time, 6,800 msec; echo time, 100 msec; T1, 150 msec; b value, 1,000 sec/mm(2)) without breath-holding. Two radiologists independently interpreted the DWIs, T2-weighted images (T2-WI), all three types of images including DWIs, T2-WIs, and fusion images at the same time (DWIs + T2-WIs + fusion) with 7-14 days' interval, and the diagnostic confidence for each patient was scored. RESULTS: The area under the curve (AUC) of the composite receiver operating characteristic (ROC) curve of DWIs + T2-WIs + fusion (0.904) was significantly higher than those of DWIs (0.720; P < .001) and T2-WIs (0.822; P < .05). Both sensitivity and specificity were higher in DWIs + T2-WIs + fusion (89.5% and 81.9%, respectively) compared with those of DWIs (72.4% and 59.0%; P < .01 and P < .001, respectively). CONCLUSIONS: Abdominal high b-value DWIs have a high sensitivity and specificity for malignant tumors when T2-WIs are referred and image fusion technique is employed, suggesting that it may potentially be a new screening tool.
RATIONALE AND OBJECTIVES: To evaluate the potential usefulness of high b-value body diffusion-weighted images (DWIs) as a screening tool in the depiction of abdominal malignant tumors. MATERIALS AND METHODS: We selected 110 abdominal magnetic resonance examinations (1.5 T; 60 men; age range, 25-90 years) with and without malignant tumors (n = 37 and n = 73, respectively). Axial DWIs were obtained by single-shot spin-echo (SE) type echo planar imaging (EPI) sequence with inversion pulse (repetition time, 6,800 msec; echo time, 100 msec; T1, 150 msec; b value, 1,000 sec/mm(2)) without breath-holding. Two radiologists independently interpreted the DWIs, T2-weighted images (T2-WI), all three types of images including DWIs, T2-WIs, and fusion images at the same time (DWIs + T2-WIs + fusion) with 7-14 days' interval, and the diagnostic confidence for each patient was scored. RESULTS: The area under the curve (AUC) of the composite receiver operating characteristic (ROC) curve of DWIs + T2-WIs + fusion (0.904) was significantly higher than those of DWIs (0.720; P < .001) and T2-WIs (0.822; P < .05). Both sensitivity and specificity were higher in DWIs + T2-WIs + fusion (89.5% and 81.9%, respectively) compared with those of DWIs (72.4% and 59.0%; P < .01 and P < .001, respectively). CONCLUSIONS: Abdominal high b-value DWIs have a high sensitivity and specificity for malignant tumors when T2-WIs are referred and image fusion technique is employed, suggesting that it may potentially be a new screening tool.
Authors: Vincent Vandecaveye; Frederik De Keyzer; Chris Verslype; Katya Op de Beeck; Mina Komuta; Baki Topal; Ilse Roebben; Didier Bielen; Tania Roskams; Frederik Nevens; Steven Dymarkowski Journal: Eur Radiol Date: 2009-05-14 Impact factor: 5.315
Authors: G Anton Decker; Mashal J Batheja; Joseph M Collins; Alvin C Silva; Kristin L Mekeel; Adyr A Moss; Cuong C Nguyen; Douglas F Lake; Laurence J Miller Journal: Gastroenterol Hepatol (N Y) Date: 2010-04
Authors: Daniel A Feeney; Leslie C Sharkey; Susan M Steward; Katherine L Bahr; Michael S Henson; Daisuke Ito; Timothy D O'Brien; Carl R Jessen; Brian D Husbands; Antonella Borgatti; Jaime F Modiano Journal: Comp Med Date: 2013-04 Impact factor: 0.982
Authors: B Paudyal; P Paudyal; Y Tsushima; N Oriuchi; M Amanuma; M Miyazaki; A Taketomi-Takahashi; Y Nakazato; K Endo Journal: Br J Radiol Date: 2009-07-20 Impact factor: 3.039