| Literature DB >> 17501468 |
Abstract
We present a model which couples the membrane with the protrusive forces of actin polymerization and contractile forces of molecular motors, such as myosin. The actin polymerization at the membrane is activated by freely diffusing membrane proteins that have a spontaneous curvature. Molecular motors are recruited to the polymerizing actin filaments, from a constant reservoir, and produce a contractile force. All the forces and variables are treated in the linear limit. Our results show that for convex membrane proteins the myosin activity gives rise to robust transverse membrane waves, similar to those observed on different cells.Entities:
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Year: 2007 PMID: 17501468 DOI: 10.1103/PhysRevLett.98.168103
Source DB: PubMed Journal: Phys Rev Lett ISSN: 0031-9007 Impact factor: 9.161