| Literature DB >> 17499454 |
Alain Fournet1, Maria Elena Ferreira, Antonieta Rojas de Arias, Isabelle Guy, Hélène Guinaudeau, Horacio Heinzen.
Abstract
Thirteen known isoquinoline alkaloids were isolated from Ocotea lancifolia, popularly known as << canela pilosa >> in Brasil and << laurel né >> by the Guarani people which means smell laurel. Their activities against the promastigote forms of three Leishmania strains and the bloodstream form of Trypanosoma cruzi were evaluated, as well as their hepatocytotoxicity. Among them, the noraporphine alkaloid (-) caaverine has shown the most interesting antiprotozoal activity against Leishmania and T. cruzi parasites.Entities:
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Year: 2007 PMID： 17499454 DOI： 10.1016/j.fitote.2007.03.003
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882