Literature DB >> 17499393

Chemotherapy of leishmaniasis. Part VII: synthesis and bioevaluation of substituted terpenyl pyrimidines.

S N Suryawanshi1, B A Bhat, Susmita Pandey, Naveen Chandra, Suman Gupta.   

Abstract

Some novel 4-N-substituted terpenyl pyrimidines 5(a-d) and 7(a-g) have been synthesized using novel synthetic methods. The compounds were screened for in vivo antileishmanial screening. When compared to 4-thiomethoxy substituted pyrimidine 2 4-N-substituted terpenyl pyrimidines 5(a-d) and 7(a-g) were found inactive.

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Year:  2007        PMID: 17499393     DOI: 10.1016/j.ejmech.2006.10.002

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  5 in total

1.  Quantitative analysis of hydrogen and chalcogen bonds in two pyrimidine-5-carbonitrile derivatives, potential DHFR inhibitors: an integrated crystallographic and theoretical study.

Authors:  Lamya H Al-Wahaibi; Kushumita Chakraborty; Nora H Al-Shaalan; Mohamed Yehya Annavi Syed Majeed; Olivier Blacque; Aamal A Al-Mutairi; Ali A El-Emam; M Judith Percino; Subbiah Thamotharan
Journal:  RSC Adv       Date:  2020-10-06       Impact factor: 4.036

Review 2.  β-Ionone: Its Occurrence and Biological Function and Metabolic Engineering.

Authors:  Antonello Paparella; Liora Shaltiel-Harpaza; Mwafaq Ibdah
Journal:  Plants (Basel)       Date:  2021-04-12

Review 3.  Ionone Is More than a Violet's Fragrance: A Review.

Authors:  Lujain Aloum; Eman Alefishat; Abdu Adem; Georg Petroianu
Journal:  Molecules       Date:  2020-12-10       Impact factor: 4.411

4.  Structural Insights of Three 2,4-Disubstituted Dihydropyrimidine-5-carbonitriles as Potential Dihydrofolate Reductase Inhibitors.

Authors:  Lamya H Al-Wahaibi; Althaf Shaik; Mohammed A Elmorsy; Mohammed S M Abdelbaky; Santiago Garcia-Granda; Subbiah Thamotharan; Vijay Thiruvenkatam; Ali A El-Emam
Journal:  Molecules       Date:  2021-05-29       Impact factor: 4.411

5.  Synthesis, antifungal activity, and QSAR studies of 1,6-dihydropyrimidine derivatives.

Authors:  Chirag Rami; Laxmanbhai Patel; Chhaganbhai N Patel; Jayshree P Parmar
Journal:  J Pharm Bioallied Sci       Date:  2013-10
  5 in total

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