Literature DB >> 1749937

Intracellular signaling by 14-hydroxy-4,14-retro-retinol.

J Buck1, F Derguini, E Levi, K Nakanishi, U Hämmerling.   

Abstract

In mammals, retinol is the precursor for retinoids, which affect various aspects of morphogenesis and development. However, B lymphocytes, although retinol-dependent, do not use retinoic acid as mediator. Retinol is metabolized by B lymphocytes and other cell lines to optically active 14-hydroxy-4,14-retro-retinol; it is this compound that mediates the growth control. Thus another second messenger molecule, in addition to retinoic acid and retinal, is derived from retinol.

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Year:  1991        PMID： 1749937     DOI： 10.1126/science.1749937

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  35 in total

Review 1.  Retinoid pathway and cancer therapeutics.

Authors:  Nathan Bushue; Yu-Jui Yvonne Wan
Journal:  Adv Drug Deliv Rev       Date:  2010-08-03       Impact factor: 15.470

Review 2.  Chemistry of the retinoid (visual) cycle.

Authors:  Philip D Kiser; Marcin Golczak; Krzysztof Palczewski
Journal:  Chem Rev       Date:  2013-07-11       Impact factor: 60.622

Review 3.  Retinol as electron carrier in redox signaling, a new frontier in vitamin A research.

Authors:  Ulrich Hammerling
Journal:  Hepatobiliary Surg Nutr       Date:  2016-02       Impact factor: 7.293

Review 4.  The mitochondrial PKCδ/retinol signal complex exerts real-time control on energy homeostasis.

Authors:  Youn-Kyung Kim; Ulrich Hammerling
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2020-01-10       Impact factor: 4.698

Review 5.  Vitamin effects on the immune system: vitamins A and D take centre stage.

Authors:  J Rodrigo Mora; Makoto Iwata; Ulrich H von Andrian
Journal:  Nat Rev Immunol       Date:  2008-09       Impact factor: 53.106

6.  Activation of retinoic acid receptors by dihydroretinoids.

Authors:  Alexander R Moise; Susana Alvarez; Marta Domínguez; Rosana Alvarez; Marcin Golczak; Glenn P Lobo; Johannes von Lintig; Angel R de Lera; Krzysztof Palczewski
Journal:  Mol Pharmacol       Date:  2009-09-21       Impact factor: 4.436

7.  4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.

Authors:  C C Achkar; F Derguini; B Blumberg; A Langston; A A Levin; J Speck; R M Evans; J Bolado; K Nakanishi; J Buck; L J Gudas
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-14       Impact factor: 11.205

8.  Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation.

Authors:  Haw-Jyh Chiu; Donald A Fischman; Ulrich Hammerling
Journal:  FASEB J       Date:  2008-08-01       Impact factor: 5.191

9.  Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase.

Authors:  Alexander R Moise; Vladimir Kuksa; Yoshikazu Imanishi; Krzysztof Palczewski
Journal:  J Biol Chem       Date:  2004-09-09       Impact factor: 5.157

10.  Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR.

Authors:  S Kitareewan; L T Burka; K B Tomer; C E Parker; L J Deterding; R D Stevens; B M Forman; D E Mais; R A Heyman; T McMorris; C Weinberger
Journal:  Mol Biol Cell       Date:  1996-08       Impact factor: 4.138
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