| Literature DB >> 17498952 |
Alan D Brown1, Mark E Bunnage, Paul A Glossop, Kim James, Rhys Jones, Charlotte A L Lane, Russell A Lewthwaite, Simon Mantell, Christelle Perros-Huguet, David A Price, Mike Trevethick, Rob Webster.
Abstract
The design and profile of a series of saligenin containing long acting beta(2)-adrenoreceptor agonists is described. Evaluation of these analogues using a guinea-pig tissue model demonstrates that analogues within this series have significantly longer durations of action than salmeterol and have the potential for a once daily profile in human.Entities:
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Year: 2007 PMID： 17498952 DOI： 10.1016/j.bmcl.2007.04.081
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823