Literature DB >> 17497163

High levels of CA125 (over 1,000 IU/ml) in patients with gynecologic disease and no malignant conditions: three cases and literature review.

Fatemeh Ghaemmaghami1, Mojgan Karimi Zarchi, Bahareh Hamedi.   

Abstract

OBJECTIVE: To report the very high serum levels of CA125 in patients with benign gynecologic disease which manifests as pelvic mass.
METHODS: Clinical data of three cases with high levels of CA125 over 1,000 IU/ml and benign gynecologic conditions were gathered. in Vali-Asr hospital.
RESULTS: Three patients were scheduled for laparatomy as ovarian cancer and leiomyosarcoma. Histologic results after laparatomy showed uterine myoma in two patients and endometrioma in a third patient.
CONCLUSION: High levels of CA125 over 1,000 IU/ml, may be showed in other gynecologic conditions with no malignancy. So, other clinical and imaging data could be helpful for differential diagnosis of these patients.

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Year:  2007        PMID: 17497163     DOI: 10.1007/s00404-007-0381-x

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  10 in total

1.  CA 125 and other tumor markers in uterine leiomyomas and their association with lesion characteristics.

Authors:  Ali Babacan; Cem Kizilaslan; Ismet Gun; Murat Muhcu; Ercument Mungen; Vedat Atay
Journal:  Int J Clin Exp Med       Date:  2014-04-15

2.  Utility of paraneoplastic antigens as biomarkers for surveillance and prediction of recurrence in ovarian cancer.

Authors:  Madhumita Chatterjee; Laura C Hurley; Nancy K Levin; Matthew Stack; Michael A Tainsky
Journal:  Cancer Biomark       Date:  2017-12-06       Impact factor: 4.388

3.  Severe adenomyosis with unexpectedly high CA-125: report of a rare case.

Authors:  Ibrahim A Abdelazim; Mohannad AbuFaza; Mohamed E S Hamed; Yerbol Bekmukhambetov; Gulmira Zhurabekova; Svetlana Shikanova
Journal:  Prz Menopauzalny       Date:  2020-10-02

4.  Premenarchal ovarian torsion and elevated CA-125.

Authors:  Jenifer D McCarthy; Kimberly M Erickson; Yolanda R Smith; Elisabeth H Quint
Journal:  J Pediatr Adolesc Gynecol       Date:  2009-07-08       Impact factor: 1.814

5.  Extremely elevated CA-125 in benign ovarian disease due to stretch of the peritoneum.

Authors:  Christine J Tolman; Tejasvini Vaid; Henk W R Schreuder
Journal:  BMJ Case Rep       Date:  2012-11-27

6.  A retrospective study of surgical treatment and outcome among women with adnexal torsion in eastern Taiwan from 2010 to 2015.

Authors:  Ci Huang; Mun-Kun Hong; Tang-Yuan Chu; Dah-Ching Ding
Journal:  PeerJ       Date:  2018-12-04       Impact factor: 2.984

7.  An optical study of drug resistance detection in endometrial cancer cells by dynamic and quantitative phase imaging.

Authors:  Tian Yao; Runyu Cao; Wen Xiao; Feng Pan; Xiaoping Li
Journal:  J Biophotonics       Date:  2019-04-02       Impact factor: 3.207

Review 8.  Liquid biopsy in ovarian cancer: Catching the silent killer before it strikes.

Authors:  Laura Feeney; Ian Jg Harley; W Glenn McCluggage; Paul B Mullan; James P Beirne
Journal:  World J Clin Oncol       Date:  2020-11-24

9.  A randomized prospective trial of the postoperative quality of life between laparoscopic uterine artery ligation and laparoscopy-assisted vaginal hysterectomy for the treatment of symptomatic uterine fibroids: clinical trial design.

Authors:  Hee Seung Kim; Jae Weon Kim; Mi-Kyung Kim; Hyun Hoon Chung; Taek Sang Lee; Yong-Tark Jeon; Yong Beom Kim; Hye Won Jeon; Young Ho Yun; Noh Hyun Park; Yong Sang Song; Soon-Beom Kang
Journal:  Trials       Date:  2009-01-29       Impact factor: 2.279

10.  Large twisted ovarian fibroma associated with Meigs' syndrome, abdominal pain and severe anemia treated by laparoscopic surgery.

Authors:  Antonio Macciò; Clelia Madeddu; Paraskevas Kotsonis; Michele Pietrangeli; Anna Maria Paoletti
Journal:  BMC Surg       Date:  2014-06-24       Impact factor: 2.102

  10 in total

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