Literature DB >> 17496568

Acute bacterial skin infections and cellulitis.

Marion Gabillot-Carré1, Jean-Claude Roujeau.   

Abstract

PURPOSE OF REVIEW: Acute bacterial skin infections are very common, with various presentations and severity. This review focuses on deep skin infections. We separate acute nonnecrotizing infections of the hypodermis (erysipelas), forms with abscesses or exudates and necrotizing fasciitis. These three types actually differ in risk factors, bacteriology, treatment and prognosis. RECENT
FINDINGS: Leg erysipelas/cellulitis occurs in more than one person/1000/year. It remains mainly due to streptococci. Foot intertrigo is an important risk factor. Necrotizing fasciitis is much rarer and usually occurs in patients with chronic diseases. Staphylococci, especially community-acquired methicillin-resistant strains in some areas, play a growing role in the intermediate form of cellulitis with abscesses and exudates. For erysipelas or noncomplicated cellulitis, antibiotic treatment at home, when feasible, is much less expensive and as effective as hospital treatment. Intermediate cases with collections and exudates often require surgical drainage. For necrotizing fasciitis early surgery remains essential in order to decrease the mortality rate.
SUMMARY: Antibiotic treatment of deep skin infections must be active on streptococci; the choice of a larger spectrum of activity depends on clinical presentation, risk factors and the burden of methicillin-resistant staphylococci in the environment.

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Year:  2007        PMID: 17496568     DOI: 10.1097/QCO.0b013e32805dfb2d

Source DB:  PubMed          Journal:  Curr Opin Infect Dis        ISSN: 0951-7375            Impact factor:   4.915


  8 in total

1.  Sivextro (Tedizolid Phosphate) Approved for the Treatment of Adults with Acute Bacterial Skin and Skin-Structure Infections.

Authors:  Loretta Fala
Journal:  Am Health Drug Benefits       Date:  2015-03

2.  Dispersal of Group A streptococcal biofilms by the cysteine protease SpeB leads to increased disease severity in a murine model.

Authors:  Kristie L Connolly; Amity L Roberts; Robert C Holder; Sean D Reid
Journal:  PLoS One       Date:  2011-04-25       Impact factor: 3.240

3.  Is Community-Acquired Methicillin-Resistant Staphylococcus aureus Coverage Needed for Cellulitis?

Authors:  Michael Horseman; John D Bowman
Journal:  Infect Dis Ther       Date:  2013-11-12

4.  Cutaneous infection and bactaeremia caused by Erwinia billingiae: a case report.

Authors:  M Prod'homme; L A Micol; S Weitsch; J-L Gassend; O Martinet; C Bellini
Journal:  New Microbes New Infect       Date:  2017-07-23

5.  Risk factors and complications of lower limb cellulitis in Africa: a systematic review.

Authors:  Frank-Leonel Tianyi; Clarence Mvalo Mbanga; Celestin Danwang; Valirie Ndip Agbor
Journal:  BMJ Open       Date:  2018-07-23       Impact factor: 2.692

6.  Calciphylaxis: A Deceiving Cellulitis.

Authors:  Sreenath Meegada; Madhavi Annakula; Tejo Challa; Prashanth Peddi
Journal:  Cureus       Date:  2019-12-30

7.  The risk of cellulitis in cirrhotic patients: a nationwide population-based study in taiwan.

Authors:  Ming-Nan Lin; Chen-Chi Tsai; Tsung-Hsing Hung; Chih-Chun Tsai
Journal:  Gut Liver       Date:  2012-10-18       Impact factor: 4.519

8.  A case report of hemolytic streptococcal gangrene in the danger triangle of the face with thrombocytopenia and hepatitis.

Authors:  Xiao-Ling Jia; Janak L Pathak; Jin-Fa Tong; Ji-Mei Su
Journal:  BMC Pediatr       Date:  2018-06-22       Impact factor: 2.125

  8 in total

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