Literature DB >> 17496

An improved method for the determination of acetylcholinesterase activity in rectal biopsy tissue from patients with Hirschsprung's disease.

G Dale, J R Bonham, K W Riley, J Wagget.   

Abstract

A method is described for the assay of acetylcholinesterase in tissue samples using the selective cholinesterase inhibitor, lysivane (10-(alpha-diethylaminopropyl) phenothiazine hydrochloride). Significantly increased enzyme activity is found in rectal biopsy specimens from patients with Hirschsprung's disease (p less than 0.001) indicating the diagnostic usefulness of the assay.

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Year:  1977        PMID： 17496     DOI： 10.1016/0009-8981(77)90247-9

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  5 in total

1.  Histochemical diagnosis of Hirschsprung's disease and a comparison of the histochemical and biochemical activity of acetylcholinesterase in rectal mucosal biopsies.

Authors:  W J Patrick; G T Besley; I I Smith
Journal:  J Clin Pathol       Date:  1980-04       Impact factor: 3.411

Review 2.  Acetylcholinesterase in Hirschsprung's disease.

Authors:  S W Moore; G Johnson
Journal:  Pediatr Surg Int       Date:  2005-03-10       Impact factor: 1.827

3.  Fractionated irradiation alters enteric neuroendocrine products.

Authors:  M F Otterson; T R Koch; Z Zhang; S C Leming; J E Moulder
Journal:  Dig Dis Sci       Date:  1995-08       Impact factor: 3.199

4.  Acetylcholinesterase activity in rectal mucosa and blood in the diagnosis of Hirschsprung's disease.

Authors:  J Yanagihara; N Iwai; T Tsuto; S Majima
Journal:  Jpn J Surg       Date:  1983-01

5.  Neonatal small left colon syndrome.

Authors:  L Rangecroft
Journal:  Arch Dis Child       Date:  1979-08       Impact factor: 3.791
  5 in total

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