| Literature DB >> 17495935 |
J J Albers1, M L Koschinsky, S M Marcovina.
Abstract
Numerous studies have suggested a role of the kidney in lipoprotein(a) (Lp(a)) catabolism, but direct evidence is still lacking. Frischmann et al. demonstrate that the marked elevation of Lp(a) observed in hemodialysis patients results from a decrease in Lp(a) clearance rather than an increase in Lp(a) production, consistent with the notion that the kidney degrades Lp(a). More studies are needed to prove the biological relevance.Entities:
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Year: 2007 PMID: 17495935 DOI: 10.1038/sj.ki.5002240
Source DB: PubMed Journal: Kidney Int ISSN: 0085-2538 Impact factor: 10.612