Literature DB >> 17493770

Cytotoxic triterpene glycosides from the sea cucumber Pseudocolochirus violaceus.

Shu-Yu Zhang1, Hai-Feng Tang, Yang-Hua Yi.   

Abstract

A new triterpene glycoside (1) along with the known intercedenside B (2) was isolated from the sea cucumber Pseudocolochirus violaceus. Glycoside 1 was elucidated as 3-O-{6-O-sodiumsulfate-3-O-methyl-beta-D-glucopyranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-[beta-D-xylopyranosyl(1-->2)]-beta-D-quinovopyranosyl-(1-->2)-4-O-sodiumsulfate-beta-D-xylopyranosyl}-16beta-acetoxy-holosta-7, 24-diene-3beta-ol on the basis of extensive spectral studies and chemical evidence. Both the glycosides exhibited significant cytotoxicity against cancer cell lines MKN-45 and HCT-116.

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Year:  2007        PMID： 17493770     DOI： 10.1016/j.fitote.2007.02.010

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  10 in total

1.  Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions.

Authors:  Qin Zhao; Zhi-dong Liu; Yong Xue; Jing-feng Wang; Hui Li; Qing-juan Tang; Yu-ming Wang; Ping Dong; Chang-hu Xue
Journal:  J Zhejiang Univ Sci B       Date:  2011-07       Impact factor: 3.066

2.  Saponins as cytotoxic agents: a review.

Authors:  Irma Podolak; Agnieszka Galanty; Danuta Sobolewska
Journal:  Phytochem Rev       Date:  2010-06-25       Impact factor: 5.374

3.  Structure elucidation of five novel isomeric saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Tim Chataway; Chris Franco
Journal:  Mar Drugs       Date:  2014-08-08       Impact factor: 5.118

4.  Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells.

Authors:  Juanjuan Wang; Hua Han; Xiangfeng Chen; Yanghua Yi; Hongxiang Sun
Journal:  Mar Drugs       Date:  2014-07-24       Impact factor: 5.118

Review 5.  Anticancer activity of sea cucumber triterpene glycosides.

Authors:  Dmitry L Aminin; Ekaterina S Menchinskaya; Evgeny A Pisliagin; Alexandra S Silchenko; Sergey A Avilov; Vladimir I Kalinin
Journal:  Mar Drugs       Date:  2015-03-06       Impact factor: 5.118

6.  Cytotoxic Screening of Marine Organisms from Persian Gulf.

Authors:  Golnaz Vaseghi; Farideh Hajakbari; Shabnam Sajjadi; Nasim Dana; Ahmad Ghasemi; Afsaneh Yegdaneh
Journal:  Adv Biomed Res       Date:  2018-07-02

7.  Discovery of novel saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Chris Franco
Journal:  Mar Drugs       Date:  2014-05-09       Impact factor: 5.118

Review 8.  Acetylated Triterpene Glycosides and Their Biological Activity from Holothuroidea Reported in the Past Six Decades.

Authors:  Yadollah Bahrami; Christopher M M Franco
Journal:  Mar Drugs       Date:  2016-08-04       Impact factor: 5.118

9.  Reduction of SCUBE3 by a new marine-derived asterosaponin leads to arrest of glioma cells in G1/S.

Authors:  Peng-Cheng Qiu; Yun-Yang Lu; Shan Zhang; Hua Li; Han Bao; Yu-Qiang Ji; Fei Fang; Hai-Feng Tang; Guang Cheng
Journal:  Oncogenesis       Date:  2020-08-06       Impact factor: 7.485

10.  Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells.

Authors:  Guang Cheng; Yu-Ye Xue; Fei Fang; Guang-Qiang Sun; Yun-Yang Lu; Yu-Qiang Ji; Peng-Cheng Qiu; Hai-Feng Tang
Journal:  Transl Cancer Res       Date:  2021-09       Impact factor: 1.241
  10 in total

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