Literature DB >> 17492936

Novel small-molecule therapy of Hodgkin lymphoma.

Daniela Buglio1, Georgios Georgakis, Anas Younes.   

Abstract

The treatment of Hodgkin lymphoma continues to be based on combination chemotherapy and radiation therapy. Although this treatment strategy produces a high cure rate, short- and long-term toxic effects continue to be problematic for young cured patients. In this review we focus on emerging novel therapies using small molecules that target specific survival pathways in the cancer cells. This approach is aimed at improving the cure rate while reducing treatment-related toxicity.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17492936     DOI: 10.1586/14737140.7.5.735

Source DB:  PubMed          Journal:  Expert Rev Anticancer Ther        ISSN: 1473-7140            Impact factor:   4.512


  4 in total

Review 1.  Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma.

Authors:  Adam Jona; Anas Younes
Journal:  Blood Rev       Date:  2010-09-15       Impact factor: 8.250

2.  Radioimmunotherapy with Tenarad, a 131I-labelled antibody fragment targeting the extra-domain A1 of tenascin-C, in patients with refractory Hodgkin's lymphoma.

Authors:  Luigi Aloj; Laura D'Ambrosio; Michela Aurilio; Anna Morisco; Ferdinando Frigeri; Corradina Caraco'; Francesca Di Gennaro; Gaetana Capobianco; Leonardo Giovannoni; Hans D Menssen; Dario Neri; Antonio Pinto; Secondo Lastoria
Journal:  Eur J Nucl Med Mol Imaging       Date:  2014-01-17       Impact factor: 9.236

3.  Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis.

Authors:  Tania Diaz; Alfons Navarro; Gerardo Ferrer; Bernat Gel; Anna Gaya; Rosa Artells; Beatriz Bellosillo; Mar Garcia-Garcia; Sergi Serrano; Antonio Martínez; Mariano Monzo
Journal:  PLoS One       Date:  2011-04-20       Impact factor: 3.240

Review 4.  Clinical Options in Relapsed or Refractory Hodgkin Lymphoma: An Updated Review.

Authors:  Roberta Fedele; Massimo Martino; Anna Grazia Recchia; Giuseppe Irrera; Massimo Gentile; Fortunato Morabito
Journal:  J Immunol Res       Date:  2015-12-16       Impact factor: 4.818

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.