BACKGROUND: Left ventricular mobile thrombi carry high risk of embolism and need early treatment in which the appropriate treatment is still controversial. Because most patients with mobile thrombi have low ejection fraction and also accompanying heart failure symptoms, decision of surgical treatment is not always easy and thus effective medical treatment is crucial. METHOD: In this paper we present, treatment and follow-up of seven patients with mobile thrombi who underwent fibrinolytic treatment between 2002 and 2006. RESULTS: In four cases, mobile thrombi disappeared completely while echocardiographically regressed to lower size with decreased mobility in the other three patients. On 6th month follow-up, complete lysis of the thrombi in six patients was observed with warfarin treatment. No major complications were seen in the patients. CONCLUSION: In case of mobile left ventricular thrombi with concomitant low ejection fraction and heart failure fibrinolytic treatment might be a therapeutic option.
BACKGROUND:Left ventricular mobile thrombi carry high risk of embolism and need early treatment in which the appropriate treatment is still controversial. Because most patients with mobile thrombi have low ejection fraction and also accompanying heart failure symptoms, decision of surgical treatment is not always easy and thus effective medical treatment is crucial. METHOD: In this paper we present, treatment and follow-up of seven patients with mobile thrombi who underwent fibrinolytic treatment between 2002 and 2006. RESULTS: In four cases, mobile thrombi disappeared completely while echocardiographically regressed to lower size with decreased mobility in the other three patients. On 6th month follow-up, complete lysis of the thrombi in six patients was observed with warfarin treatment. No major complications were seen in the patients. CONCLUSION: In case of mobile left ventricular thrombi with concomitant low ejection fraction and heart failure fibrinolytic treatment might be a therapeutic option.
Authors: Philippe Meurin; Jean Yves Tabet; Nathalie Renaud; Hélène Weber; Anne Grosdemouge; Claude Bourmayan; Ahmed Ben Driss Journal: Int J Cardiol Date: 2005-02-15 Impact factor: 4.164
Authors: A Keren; S Goldberg; S Gottlieb; J Klein; C Schuger; A Medina; D Tzivoni; S Stern Journal: J Am Coll Cardiol Date: 1990-03-15 Impact factor: 24.094
Authors: Jürgen Leick; Sebastian Szardien; Christoph Liebetrau; Matthias Willmer; Ulrich Fischer-Rasokat; Jörg Kempfert; Holger Nef; Andreas Rolf; Thomas Walther; Christian Hamm; Helge Möllmann Journal: Clin Res Cardiol Date: 2013-04-14 Impact factor: 5.460