Literature DB >> 17491677

Type 1 diabetes and NKT cells: a report on the 3rd International Workshop on NKT cells and CD1-mediated antigen presentation, September 2004, Heron Island, QLD, Australia.

Julie M Fletcher1, Margaret A Jordan, Alan G Baxter.   

Abstract

NKT cells play a major role in regulating the vigor and character of a broad range of immune responses. Defects in NKT cell numbers and function have been associated with type 1 diabetes, especially in the NOD mouse model. The 3rd International Workshop on NKT Cells and CD1-Mediated Antigen Presentation provided an opportunity for researchers in the field of NKT cell biology to discuss their latest results, many of which have direct relevance to understanding the etiology and pathogenesis of diabetes.

Entities:  

Year:  2004        PMID: 17491677      PMCID: PMC1783544          DOI: 10.1900/RDS.2004.1.141

Source DB:  PubMed          Journal:  Rev Diabet Stud        ISSN: 1613-6071


  26 in total

1.  Cytometric and functional analyses of NK and NKT cell deficiencies in NOD mice.

Authors:  L D Poulton; M J Smyth; C G Hawke; P Silveira; D Shepherd; O V Naidenko; D I Godfrey; A G Baxter
Journal:  Int Immunol       Date:  2001-07       Impact factor: 4.823

2.  CD1d-restricted NKT cells: an interstrain comparison.

Authors:  K J Hammond; D G Pellicci; L D Poulton; O V Naidenko; A A Scalzo; A G Baxter; D I Godfrey
Journal:  J Immunol       Date:  2001-08-01       Impact factor: 5.422

3.  Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse.

Authors:  F D Shi; M Flodstrom; B Balasa; S H Kim; K Van Gunst; J L Strominger; S B Wilson; N Sarvetnick
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-05       Impact factor: 11.205

4.  Association between alphabetaTCR+CD4-CD8- T-cell deficiency and IDDM in NOD/Lt mice.

Authors:  A G Baxter; S J Kinder; K J Hammond; R Scollay; D I Godfrey
Journal:  Diabetes       Date:  1997-04       Impact factor: 9.461

5.  Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases.

Authors:  D Phaneuf; N Wakamatsu; J Q Huang; A Borowski; A C Peterson; S R Fortunato; G Ritter; S A Igdoura; C R Morales; G Benoit; B R Akerman; D Leclerc; N Hanai; J D Marth; J M Trasler; R A Gravel
Journal:  Hum Mol Genet       Date:  1996-01       Impact factor: 6.150

6.  CD1-restricted NK T cells protect nonobese diabetic mice from developing diabetes.

Authors:  B Wang; Y B Geng; C R Wang
Journal:  J Exp Med       Date:  2001-08-06       Impact factor: 14.307

7.  In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers.

Authors:  K Benlagha; A Weiss; A Beavis; L Teyton; A Bendelac
Journal:  J Exp Med       Date:  2000-06-05       Impact factor: 14.307

8.  alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

Authors:  K J Hammond; L D Poulton; L J Palmisano; P A Silveira; D I Godfrey; A G Baxter
Journal:  J Exp Med       Date:  1998-04-06       Impact factor: 14.307

9.  Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers.

Authors:  J L Matsuda; O V Naidenko; L Gapin; T Nakayama; M Taniguchi; C R Wang; Y Koezuka; M Kronenberg
Journal:  J Exp Med       Date:  2000-09-04       Impact factor: 14.307

10.  Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

Authors:  A Lehuen; O Lantz; L Beaudoin; V Laloux; C Carnaud; A Bendelac; J F Bach; R C Monteiro
Journal:  J Exp Med       Date:  1998-11-16       Impact factor: 14.307

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