OBJECTIVES: The aim of the study was to investigate the presence of serum antibodies to different Leptospira serogroups in dogs with a clinical diagnosis of leptospirosis in southern Germany and to compare seroreactivity to different serogroups with history, clinical signs, laboratory findings and survival rate. METHODS: In this study, the data of 42 dogs with the diagnosis of leptospirosis were evaluated retrospectively. Dogs were presented to the Small Animal Medicine Teaching Hospital (Medizinische Kleintierklinik) of the Ludwig Maximilians University Munich, Germany, between 1990 to 2003. RESULTS: Reactivity to the serogroup grippotyphosa (13/42) was most frequently present, followed by reactivity to the serogroup saxkoebing (10/42). There was no difference in the clinical picture and the laboratory changes between dogs whose sera were reactive to different serogroups. CLINICAL SIGNIFICANCE: Most of the dogs with leptospirosis in southern Germany had sera reacting to serogroups other than icterohaemorrhagiae and canicola, which are contained in the vaccine. Thus, currently available vaccines in Europe do not protect against the most common Leptospira organisms associated with clinical disease.
OBJECTIVES: The aim of the study was to investigate the presence of serum antibodies to different Leptospira serogroups in dogs with a clinical diagnosis of leptospirosis in southern Germany and to compare seroreactivity to different serogroups with history, clinical signs, laboratory findings and survival rate. METHODS: In this study, the data of 42 dogs with the diagnosis of leptospirosis were evaluated retrospectively. Dogs were presented to the Small Animal Medicine Teaching Hospital (Medizinische Kleintierklinik) of the Ludwig Maximilians University Munich, Germany, between 1990 to 2003. RESULTS: Reactivity to the serogroup grippotyphosa (13/42) was most frequently present, followed by reactivity to the serogroup saxkoebing (10/42). There was no difference in the clinical picture and the laboratory changes between dogs whose sera were reactive to different serogroups. CLINICAL SIGNIFICANCE: Most of the dogs with leptospirosis in southern Germany had sera reacting to serogroups other than icterohaemorrhagiae and canicola, which are contained in the vaccine. Thus, currently available vaccines in Europe do not protect against the most common Leptospira organisms associated with clinical disease.
Authors: Sharon Y A M Villanueva; Hirokazu Ezoe; Rubelia A Baterna; Yasutake Yanagihara; Maki Muto; Nobuo Koizumi; Takashi Fukui; Yoshihiro Okamoto; Toshiyuki Masuzawa; Lolita L Cavinta; Nina G Gloriani; Shin-ichi Yoshida Journal: Am J Trop Med Hyg Date: 2010-05 Impact factor: 2.345
Authors: Stephen A Felt; Momtaz O Wasfy; Wael F El-Tras; Ahmed Samir; Bassem Abdel Rahaman; Marie Boshra; Tina M Parker; Mahmoud Essam Hatem; Ahmed Ahmed El-Bassiouny; Clinton K Murray; Guillermo Pimentel Journal: Am J Trop Med Hyg Date: 2011-03 Impact factor: 2.345
Authors: Anna Rettinger; Inke Krupka; Karola Grünwald; Viktor Dyachenko; Volker Fingerle; Regina Konrad; Heribert Raschel; Ulrich Busch; Andreas Sing; Reinhard K Straubinger; Ingrid Huber Journal: BMC Microbiol Date: 2012-08-27 Impact factor: 3.605