AIM: To describe cardiac surgery, survival and outcomes for low-birthweight (< or = 2500 g) infants undergoing surgery for congenital heart disease. METHODS: Using data from a prospectively collected population-based database of admissions to neonatal intensive care units in New South Wales and the Australian Capital Territory, we identified all low-birthweight infants undergoing cardiac surgery between 1992 and 2001. Infants with only a persistent ductus arteriosus were excluded. Two-year cardiac and neurodevelopmental outcome data were sought from hospital medical records. RESULTS: A total of 121 low-birthweight infants underwent cardiac surgery, of whom 34% had a congenital syndrome or non-cardiac birth defect. Most (81%) underwent a palliative surgical procedure in the neonatal period. There were 19 early (15.7%) and 19 late deaths giving a 2-year mortality of 31%. Factors associated with mortality included birthweight below 1500 g (P = 0.006), low weight at surgery (P = 0.028) and Apgar score at 1 min (P = 0.019). No single factor predicted 30-day mortality. By 2 years of age, 27 (33% of survivors) were known to have neurodevelopmental delay. Although 22 children are known to be developing normally, the neurodevelopmental status of 34 children was not known. CONCLUSIONS: These surgical data were comparable to previous single-institution studies. This group had a high risk of disability due to prematurity, low birthweight and associated conditions. There is a need to prospectively assess and manage neurodevelopmental outcomes in this group.
AIM: To describe cardiac surgery, survival and outcomes for low-birthweight (< or = 2500 g) infants undergoing surgery for congenital heart disease. METHODS: Using data from a prospectively collected population-based database of admissions to neonatal intensive care units in New South Wales and the Australian Capital Territory, we identified all low-birthweight infants undergoing cardiac surgery between 1992 and 2001. Infants with only a persistent ductus arteriosus were excluded. Two-year cardiac and neurodevelopmental outcome data were sought from hospital medical records. RESULTS: A total of 121 low-birthweight infants underwent cardiac surgery, of whom 34% had a congenital syndrome or non-cardiac birth defect. Most (81%) underwent a palliative surgical procedure in the neonatal period. There were 19 early (15.7%) and 19 late deaths giving a 2-year mortality of 31%. Factors associated with mortality included birthweight below 1500 g (P = 0.006), low weight at surgery (P = 0.028) and Apgar score at 1 min (P = 0.019). No single factor predicted 30-day mortality. By 2 years of age, 27 (33% of survivors) were known to have neurodevelopmental delay. Although 22 children are known to be developing normally, the neurodevelopmental status of 34 children was not known. CONCLUSIONS: These surgical data were comparable to previous single-institution studies. This group had a high risk of disability due to prematurity, low birthweight and associated conditions. There is a need to prospectively assess and manage neurodevelopmental outcomes in this group.
Authors: David Kalfa; Ganga Krishnamurthy; Jennifer Duchon; Marc Najjar; Stéphanie Levasseur; Paul Chai; Jonathan Chen; Jan Quaegebeur; Emile Bacha Journal: J Thorac Cardiovasc Surg Date: 2014-07-31 Impact factor: 5.209
Authors: Michael Salna; Paul J Chai; David Kalfa; Yuki Nakamura; Ganga Krishnamurthy; Jan M Quaegebeur; Marc Najjar; Amee Shah; Stephanie Levasseur; Brett R Anderson; Emile A Bacha Journal: Semin Thorac Cardiovasc Surg Date: 2018-04-02
Authors: Athina Pappas; Seetha Shankaran; Nellie I Hansen; Edward F Bell; Barbara J Stoll; Abbot R Laptook; Michele C Walsh; Abhik Das; Rebecca Bara; Ellen C Hale; Nancy S Newman; Nansi S Boghossian; Jeffrey C Murray; C Michael Cotten; Ira Adams-Chapman; Shannon Hamrick; Rosemary D Higgins Journal: Pediatr Cardiol Date: 2012-05-30 Impact factor: 1.655
Authors: Angelo Polito; Simone Piga; Paola E Cogo; Carlo Corchia; Virgilio Carnielli; Monica Da Frè; Domenico Di Lallo; Isabella Favia; Luigi Gagliardi; Francesco Macagno; Silvana Miniaci; Marina Cuttini Journal: Intensive Care Med Date: 2013-03-28 Impact factor: 17.440
Authors: Wendy N Nembhard; Jason L Salemi; Melissa L Loscalzo; Tao Wang; Kimberlea W Hauser Journal: Pediatr Cardiol Date: 2009-05-02 Impact factor: 1.655
Authors: Charlene M T Robertson; Reg S Sauve; Ari R Joffe; Gwen Y Alton; Diane M Moddemann; Patricia M Blakley; Anne R Synnes; Irina A Dinu; Joyce R Harder; Reeni Soni; Jaya P Bodani; Ashok P Kakadekar; John D Dyck; Derek G Human; David B Ross; Ivan M Rebeyka Journal: Cardiol Res Pract Date: 2011-05-08 Impact factor: 1.866
Authors: Po-Yin Cheung; Morteza Hajihosseini; Irina A Dinu; Heather Switzer; Ari R Joffe; Gwen Y Bond; Charlene M T Robertson Journal: Front Pediatr Date: 2021-01-28 Impact factor: 3.418