Literature DB >> 17488400

Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification.

J Röwert-Huber1, M J Patel, T Forschner, C Ulrich, J Eberle, H Kerl, W Sterry, E Stockfleth.   

Abstract

The term actinic keratosis (AK) describes a sun-induced, clinical erythematous lesion covered with scale, but does not provide an understanding of the biology or histopathology of the lesion. Consequently, several classification systems for AK have been suggested, but as yet no consensus has been reached. These systems strive to correlate the pathological and clinical features to better provide physicians with the most accurate information to enable correct decisions to be made regarding treatments, Prognosis and metastatic potential. AK is a clinical description that has a histological diagnosis consistent with squamous cell carcinoma (SCC) in situ. We recommend an AK classification system that describes these lesions as squamous cell carcinomas (SCCs), using the terminology 'early in situ SCC Type AK I', 'early in situ SCC type AK II' and 'in situ SCC Type AK III', there by giving clinicians better guidance for diagnosis and specific treatment recommendations.

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Year:  2007        PMID: 17488400     DOI: 10.1111/j.1365-2133.2007.07860.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  53 in total

Review 1.  [Actinic keratosis, Bowen's disease, keratoacanthoma and squamous cell carcinoma of the skin].

Authors:  M Majores; E Bierhoff
Journal:  Pathologe       Date:  2015-02       Impact factor: 1.011

2.  [Precancerous tumors and carcinomas in situ of the skin].

Authors:  D Krüger-Corcoran; S Vandersee; E Stockfleth
Journal:  Internist (Berl)       Date:  2013-06       Impact factor: 0.743

Review 3.  [Actinic keratoses. Pathogenesis, clinical aspect and modern therapeutic options].

Authors:  T Strunk; R-M Szeimies
Journal:  Hautarzt       Date:  2014-03       Impact factor: 0.751

4.  Correlation of telomere length to malignancy potential in non-melanoma skin cancers.

Authors:  Hanae Yamada-Hishida; Yoshimasa Nobeyama; Hidemi Nakagawa
Journal:  Oncol Lett       Date:  2017-10-26       Impact factor: 2.967

5.  Single Ablative Fractional Resurfacing Laser Treatment For Forearm Actinic Keratoses: 6-Month Follow-Up Data From An Intrapatient Comparison Between Treated and Untreated Sites.

Authors:  Roy Chen; Jeffrey J Wargo; Amy Williams; Elizabeth Cates; Dan F Spandau; Christina Knisely; Jeffrey B Travers
Journal:  Lasers Surg Med       Date:  2019-11-17       Impact factor: 4.025

6.  Topical treatment of actinic keratoses with potassium dobesilate 5% cream. a preliminary open-label study.

Authors:  Pedro Cuevas Sánchez; W Espinoza; C Pérez; J Angulo; G Giménez-Gallego
Journal:  Eur J Med Res       Date:  2011-02-24       Impact factor: 2.175

7.  An update on nonmelanoma skin cancer.

Authors:  Rita V Patel; Amylynne Frankel; Gary Goldenberg
Journal:  J Clin Aesthet Dermatol       Date:  2011-02

Review 8.  [Actinic keratoses].

Authors:  T Hommel; R-M Szeimies
Journal:  Hautarzt       Date:  2016-11       Impact factor: 0.751

Review 9.  Retinoids for prevention and treatment of actinic keratosis.

Authors:  Mayra Ianhez; Luiz Fernando Fróes Fleury; Hélio Amante Miot; Edileia Bagatin
Journal:  An Bras Dermatol       Date:  2013 Jul-Aug       Impact factor: 1.896

10.  Mucin1 expression in focal epidermal dysplasia of actinic keratosis.

Authors:  Enrique Arciniegas; Luz Marina Carrillo; Héctor Rojas; Richard Ramírez; Oscar Reyes; Ambar Suárez; Fabiana Ortega
Journal:  Ann Transl Med       Date:  2015-10
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