Literature DB >> 17486294

Changing patterns of thyroid carcinoma.

B Dijkstra1, R S Prichard, A Lee, L M Kelly, P P A Smyth, T Crotty, E W McDermott, A D K Hill, N O'Higgins.   

Abstract

BACKGROUND: To assess changing trends in histological types of thyroid cancer in an Irish hospital over the past 30 years.
METHODS: Biographical data, tumour characteristics, treatment and outcome from 190 patients with thyroid carcinoma from 1970 to 2000 were reviewed retrospectively.
RESULTS: Detailed records of 190 patients with thyroid cancer were identified with a mean age at presentation of 50 years. From 1970 to 1979 the distribution of histological types was: papillary carcinoma; 9 patients (4.7%), follicular; 17 patients (8.9%), anaplastic; 9 patients (4.7%), medullary; 1 patient (0.5%) and lymphoma; 1 patient (0.5%). From 1980 to 1989 papillary carcinoma accounted for 32 patients (16.8%), follicular; 14 patients (7.3%), anaplastic; 13 patients (6.8%), medullary; 7 patients (3.7%) and lymphoma; 5 patients (2.6%). From 1990 to 1999 papillary cancer accounted for 48 patients (25.2%), follicular; 14 patients (7.3%), anaplastic; 8 patients (4.2%), medullary; 7 patients (3.7%) and lymphoma; 5 patients (2.6%). Survival rates were significantly better for those aged less than 45 years (P < 0.0001), female sex (P < 0.01) and those with papillary carcinoma (P < 0.01).
CONCLUSIONS: This study demonstrated a significant increase in the incidence of papillary carcinoma. This may be related to increasing dietary iodine intake and may be significant as papillary carcinoma is associated with a more favourable prognosis.

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Year:  2007        PMID: 17486294     DOI: 10.1007/s11845-007-0041-y

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  24 in total

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3.  Iodine intake in Ireland--an update.

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Journal:  Ir J Med Sci       Date:  1988-12       Impact factor: 1.568

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8.  2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.

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