Literature DB >> 17485844

Improvement of the antitumor activity of black currant polysaccharide by an enzymatic treatment.

Ryoji Takata1, Takaaki Yanai, Reiko Yamamoto, Tomonori Konno.   

Abstract

A polysaccharide-rich substance isolated from black currant, named cassis polysaccharide (CAPS), was partially digested with beta-galactosidase from Aspergillus oryzae and its immunostimulatory activity was investigated. The in vitro cytokine-inducing effect of CAPS on RAW264 cells was gradually decreased along with lowering of the average MW of CAPS. In vivo, partially digested CAPS with a mean MW of approximately 20,000 showed the most potent antitumor activity against Ehrlich carcinoma in mice.

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Year:  2007        PMID： 17485844     DOI： 10.1271/bbb.60725

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  3 in total

1.  Polysaccharide from black currant (Ribes nigrum L.) stimulates dendritic cells through TLR4 signaling.

Authors:  Hiroshi Ashigai; Yuta Komano; Guanying Wang; Yasuji Kawachi; Kazuko Sunaga; Reiko Yamamoto; Ryoji Takata; Mika Miyake; Takaaki Yanai
Journal:  Biosci Microbiota Food Health       Date:  2017-07-04

2.  Preparation, characterization, antioxidant and antiglycation activities of selenized polysaccharides from blackcurrant.

Authors:  Changzong Wu; Meimei Zhao; Xueying Bu; Ziya Qing; Libo Wang; Yaqin Xu; Yu Yang; Jingwen Bai
Journal:  RSC Adv       Date:  2020-09-02       Impact factor: 4.036

3.  Effect of administrating polysaccharide from black currant (Ribes nigrum L.) on atopic dermatitis in NC/Nga mice.

Authors:  Hiroshi Ashigai; Yuta Komano; Guanying Wang; Yasuji Kawachi; Kazuko Sunaga; Reiko Yamamoto; Ryoji Takata; Mika Miyake; Takaaki Yanai
Journal:  Biosci Microbiota Food Health       Date:  2017-11-16
  3 in total

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