Literature DB >> 17485381

Notch signaling and its role in breast cancer.

Fangting Wu1, Alan Stutzman, Yin-Yuan Mo.   

Abstract

The Notch signaling plays a key role in cell differentiation, survival, and proliferation through diverse mechanisms. Thus, alterations of the Notch signaling can lead to a variety of disorders including human malignancies. In this review, we will focus on recent advancements in identification of aberrant Notch signaling in cancer, and the possible underlying mechanisms in breast cancer. We will also highlight the therapeutic potential of targeting Notch for cancer treatment.

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Year:  2007        PMID： 17485381     DOI： 10.2741/2394

Source DB:  PubMed          Journal:  Front Biosci        ISSN： 1093-4715


  27 in total

Review 1.  Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy.

Authors:  Li Li; Ping Tang; Shun Li; Xiang Qin; Hong Yang; Chunhui Wu; Yiyao Liu
Journal:  Med Oncol       Date:  2017-09-16       Impact factor: 3.064

Review 2.  Targeting cancer stem cell pathways for cancer therapy.

Authors:  Liqun Yang; Pengfei Shi; Gaichao Zhao; Jie Xu; Wen Peng; Jiayi Zhang; Guanghui Zhang; Xiaowen Wang; Zhen Dong; Fei Chen; Hongjuan Cui
Journal:  Signal Transduct Target Ther       Date:  2020-02-07

Review 3.  Role of Notch and its oncogenic signaling crosstalk in breast cancer.

Authors:  Shanchun Guo; Mingli Liu; Ruben R Gonzalez-Perez
Journal:  Biochim Biophys Acta       Date:  2010-12-28

4.  Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells.

Authors:  Brandi B Knight; Gabriela M Oprea-Ilies; Arumugam Nagalingam; Lily Yang; Cynthia Cohen; Neeraj K Saxena; Dipali Sharma
Journal:  Endocr Relat Cancer       Date:  2011-07-01       Impact factor: 5.678

5.  NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.

Authors:  Yi-Ping Fu; Hege Edvardsen; Alpana Kaushiva; Juan P Arhancet; Tiffany M Howe; Indu Kohaar; Patricia Porter-Gill; Anushi Shah; Hege Landmark-Høyvik; Sophie D Fosså; Stefan Ambs; Bjørn Naume; Anne-Lise Børresen-Dale; Vessela N Kristensen; Ludmila Prokunina-Olsson
Journal:  Mol Cancer       Date:  2010-05-19       Impact factor: 27.401

6.  Effect of Trastuzumab on Notch-1 Signaling Pathway in Breast Cancer SK-BR3 Cells.

Authors:  Ming Han; Hua-Yu Deng; Rong Jiang
Journal:  Chin J Cancer Res       Date:  2012-09       Impact factor: 5.087

7.  The role of the PTEN/AKT Pathway in NOTCH1-induced leukemia.

Authors:  Teresa Palomero; Maria Dominguez; Adolfo A Ferrando
Journal:  Cell Cycle       Date:  2008-02-19       Impact factor: 4.534

8.  Combination treatment of all-trans retinoic acid (ATRA) and γ-secretase inhibitor (DAPT) cause growth inhibition and apoptosis induction in the human gastric cancer cell line.

Authors:  Elham Patrad; Ali Niapour; Faris Farassati; Mojtaba Amani
Journal:  Cytotechnology       Date:  2018-02-07       Impact factor: 2.058

9.  The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1.

Authors:  Roy Barco; Christina B Garcia; Josiane E Eid
Journal:  PLoS One       Date:  2009-04-01       Impact factor: 3.240

10.  Postmenopausal estrogen and progestin effects on the serum proteome.

Authors:  Sharon J Pitteri; Samir M Hanash; Aaron Aragaki; Lynn M Amon; Lin Chen; Tina Busald Buson; Sophie Paczesny; Hiroyuki Katayama; Hong Wang; Melissa M Johnson; Qing Zhang; Martin McIntosh; Pei Wang; Charles Kooperberg; Jacques E Rossouw; Rebecca D Jackson; Joann E Manson; Judith Hsia; Simin Liu; Lisa Martin; Ross L Prentice
Journal:  Genome Med       Date:  2009-12-24       Impact factor: 11.117
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