Literature DB >> 17483714

High prevalence of pulmonary hypertension in children with sickle cell disease.

Stephen C Nelson1, Beverly B Adade, Elizabeth A McDonough, Kristin L Moquist, Jane M Hennessy.   

Abstract

Pulmonary hypertension (PHT) affects approximately 30% of adults with sickle cell disease. Adults with PHT have a significantly higher mortality rate. We report the results of a prospective study of the prevalence of PHT among children with sickle cell disease. In our cohort, 31% of children>or=10 years of age have evidence of PHT by Doppler echocardiography. Factors associated with the presence of PHT are male sex and elevated reticulocyte count. We recommend screening all children for PHT starting at the age of 10 years.

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Year:  2007        PMID： 17483714     DOI： 10.1097/MPH.0b013e31805d8f32

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN： 1077-4114            Impact factor:   1.289


  16 in total

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Review 7.  Pulmonary arterial hypertension in children: a medical update.

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Authors:  Victor R Gordeuk; Andrew Campbell; Sohail Rana; Mehdi Nouraie; Xiaomei Niu; Caterina P Minniti; Craig Sable; Deepika Darbari; Niti Dham; Onyinye Onyekwere; Tatiana Ammosova; Sergei Nekhai; Gregory J Kato; Mark T Gladwin; Oswaldo L Castro
Journal:  Blood       Date:  2009-09-01       Impact factor: 22.113

10.  Doppler echocardiographic assessment of pulmonary artery pressure in children with sickle cell anaemia.

Authors:  Moriam Omolola Lamina; Barakat Adeola Animasahun; Ijeoma Nnena Akinwumi; Olisamedua Fidelis Njokanma
Journal:  Cardiovasc Diagn Ther       Date:  2019-06
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