Literature DB >> 17483484

Synthesis of glycerol phosphate lipoteichoic acid in Staphylococcus aureus.

Angelika Gründling1, Olaf Schneewind.   

Abstract

Lipoteichoic acid (LTA), a glycerol phosphate surface polymer, is a component of the envelope of Gram-positive bacteria. However, the molecular basis for its synthesis or function is not known. Here we report that Staphylococcus aureus LtaS synthesizes glycerol phosphate LTA. Construction of a mutant S. aureus strain with inducible ltaS expression revealed that LTA synthesis is required for bacterial growth and cell division. An ltaS homologue of Bacillus subtilis restored LTA synthesis and the growth of ltaS mutant staphylococci. Thus, LtaS inhibition can be used as a target to treat human infections caused by antibiotic-resistant S. aureus or other bacterial pathogens.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17483484      PMCID： PMC1895975          DOI： 10.1073/pnas.0701821104

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  54 in total

1.  An efficient recombination system for chromosome engineering in Escherichia coli.

Authors:  D Yu; H M Ellis; E C Lee; N A Jenkins; N G Copeland; D L Court
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

2.  Essential Bacillus subtilis genes.

Authors:  K Kobayashi; S D Ehrlich; A Albertini; G Amati; K K Andersen; M Arnaud; K Asai; S Ashikaga; S Aymerich; P Bessieres; F Boland; S C Brignell; S Bron; K Bunai; J Chapuis; L C Christiansen; A Danchin; M Débarbouille; E Dervyn; E Deuerling; K Devine; S K Devine; O Dreesen; J Errington; S Fillinger; S J Foster; Y Fujita; A Galizzi; R Gardan; C Eschevins; T Fukushima; K Haga; C R Harwood; M Hecker; D Hosoya; M F Hullo; H Kakeshita; D Karamata; Y Kasahara; F Kawamura; K Koga; P Koski; R Kuwana; D Imamura; M Ishimaru; S Ishikawa; I Ishio; D Le Coq; A Masson; C Mauël; R Meima; R P Mellado; A Moir; S Moriya; E Nagakawa; H Nanamiya; S Nakai; P Nygaard; M Ogura; T Ohanan; M O'Reilly; M O'Rourke; Z Pragai; H M Pooley; G Rapoport; J P Rawlins; L A Rivas; C Rivolta; A Sadaie; Y Sadaie; M Sarvas; T Sato; H H Saxild; E Scanlan; W Schumann; J F M L Seegers; J Sekiguchi; A Sekowska; S J Séror; M Simon; P Stragier; R Studer; H Takamatsu; T Tanaka; M Takeuchi; H B Thomaides; V Vagner; J M van Dijl; K Watabe; A Wipat; H Yamamoto; M Yamamoto; Y Yamamoto; K Yamane; K Yata; K Yoshida; H Yoshikawa; U Zuber; N Ogasawara
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-07       Impact factor: 11.205

3.  Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999.

Authors:  D J Diekema; M A Pfaller; F J Schmitz; J Smayevsky; J Bell; R N Jones; M Beach
Journal:  Clin Infect Dis       Date:  2001-05-15       Impact factor: 9.079

4.  Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.

Authors:  D J Tipper; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1965-10       Impact factor: 11.205

5.  Biosynthesis of the glycolipid anchor in lipoteichoic acid of Staphylococcus aureus RN4220: role of YpfP, the diglucosyldiacylglycerol synthase.

Authors:  M Y Kiriukhin; D V Debabov; D L Shinabarger; F C Neuhaus
Journal:  J Bacteriol       Date:  2001-06       Impact factor: 3.490

6.  In vitro bactericidal activities of daptomycin against Staphylococcus aureus and Enterococcus faecalis are not mediated by inhibition of lipoteichoic acid biosynthesis.

Authors:  Valerie Laganas; Jeffrey Alder; Jared A Silverman
Journal:  Antimicrob Agents Chemother       Date:  2003-08       Impact factor: 5.191

7.  Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections.

Authors:  Christopher Weidenmaier; John F Kokai-Kun; Sascha A Kristian; Tanya Chanturiya; Hubert Kalbacher; Matthias Gross; Graeme Nicholson; Birgid Neumeister; James J Mond; Andreas Peschel
Journal:  Nat Med       Date:  2004-02-01       Impact factor: 53.440

8.  Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus.

Authors:  Linda M Weigel; Don B Clewell; Steven R Gill; Nancye C Clark; Linda K McDougal; Susan E Flannagan; James F Kolonay; Jyoti Shetty; George E Killgore; Fred C Tenover
Journal:  Science       Date:  2003-11-28       Impact factor: 47.728

Review 9.  A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria.

Authors:  Francis C Neuhaus; James Baddiley
Journal:  Microbiol Mol Biol Rev       Date:  2003-12       Impact factor: 11.056

10.  The occurrence of polyglycerophosphate as an antigenic component of various gram-positive bacterial species.

Authors:  M McCARTY
Journal:  J Exp Med       Date:  1959-04-01       Impact factor: 14.307
View more
  121 in total

1.  ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.

Authors:  Matthew B Frankel; Brandon M Wojcik; Andrea C DeDent; Dominique M Missiakas; Olaf Schneewind
Journal:  Mol Microbiol       Date:  2010-10       Impact factor: 3.501

2.  Determinants of murein hydrolase targeting to cross-wall of Staphylococcus aureus peptidoglycan.

Authors:  Matthew B Frankel; Olaf Schneewind
Journal:  J Biol Chem       Date:  2012-02-02       Impact factor: 5.157

3.  Expression and characterization of a Mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis: potential target against mycoplasma infections.

Authors:  Eduardo Andrés; Núria Martínez; Antoni Planas
Journal:  J Biol Chem       Date:  2011-08-11       Impact factor: 5.157

4.  The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection.

Authors:  Hideki Hara; Sergey S Seregin; Dahai Yang; Koichi Fukase; Mathias Chamaillard; Emad S Alnemri; Naohiro Inohara; Grace Y Chen; Gabriel Núñez
Journal:  Cell       Date:  2018-11-01       Impact factor: 41.582

Review 5.  Understanding the significance of Staphylococcus epidermidis bacteremia in babies and children.

Authors:  Gordon Y C Cheung; Michael Otto
Journal:  Curr Opin Infect Dis       Date:  2010-06       Impact factor: 4.915

6.  ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.

Authors:  Kathrin Schirner; Laura K Stone; Suzanne Walker
Journal:  ACS Chem Biol       Date:  2011-02-15       Impact factor: 5.100

7.  Lysostaphin Lysibody Leads to Effective Opsonization and Killing of Methicillin-Resistant Staphylococcus aureus in a Murine Model.

Authors:  Assaf Raz; Anna Serrano; Maneesha Thaker; Tricia Alston; Vincent A Fischetti
Journal:  Antimicrob Agents Chemother       Date:  2018-09-24       Impact factor: 5.191

8.  Synthesis of CDP-activated ribitol for teichoic acid precursors in Streptococcus pneumoniae.

Authors:  Stefanie Baur; Jon Marles-Wright; Stephan Buckenmaier; Richard J Lewis; Waldemar Vollmer
Journal:  J Bacteriol       Date:  2008-12-12       Impact factor: 3.490

9.  Pleiotropic roles of polyglycerolphosphate synthase of lipoteichoic acid in growth of Staphylococcus aureus cells.

Authors:  Yusuke Oku; Kenji Kurokawa; Miki Matsuo; Sakuo Yamada; Bok-Luel Lee; Kazuhisa Sekimizu
Journal:  J Bacteriol       Date:  2008-10-24       Impact factor: 3.490

10.  Genome-Wide Identification of Virulence Genes in Erysipelothrix rhusiopathiae: Use of a Mutant Deficient in a tagF Homolog as a Safe Oral Vaccine against Swine Erysipelas.

Authors:  Yoshihiro Shimoji; Yohsuke Ogawa; Manae Tsukio; Kazumasa Shiraiwa; Sayaka Nishikawa; Masahiro Eguchi
Journal:  Infect Immun       Date:  2019-11-18       Impact factor: 3.441
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.