Literature DB >> 17482537

Vitamins and aging: pathways to NAD+ synthesis.

John M Denu1.   

Abstract

Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis. In this issue, Belenky et al. (2007) report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacetylase activity and life span in yeast. The ability of nicotinamide riboside to enhance life span does not depend on calorie restriction.

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Year:  2007        PMID: 17482537     DOI: 10.1016/j.cell.2007.04.023

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  21 in total

1.  Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer.

Authors:  Antonio F Santidrian; Sarah E LeBoeuf; Erik D Wold; Melissa Ritland; Jane S Forsyth; Brunhilde H Felding
Journal:  DNA Repair (Amst)       Date:  2014-09-26

2.  Regulation of histone acetylation in the hippocampus of chronically stressed rats: a potential role of sirtuins.

Authors:  C L Ferland; L A Schrader
Journal:  Neuroscience       Date:  2010-11-05       Impact factor: 3.590

3.  Respected Sir(2): magic target for diabetes.

Authors:  Pratibha V Nerurkar; Vivek R Nerurkar
Journal:  Cellscience       Date:  2008-04-27

Review 4.  NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.

Authors:  Hassina Massudi; Ross Grant; Gilles J Guillemin; Nady Braidy
Journal:  Redox Rep       Date:  2012       Impact factor: 4.412

5.  Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes.

Authors:  Chiao-Po Hsu; Shinichi Oka; Dan Shao; Nirmala Hariharan; Junichi Sadoshima
Journal:  Circ Res       Date:  2009-08-06       Impact factor: 17.367

6.  Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae.

Authors:  Brian C Smith; Mark A Anderson; Kelly A Hoadley; James L Keck; W Wallace Cleland; John M Denu
Journal:  Biochemistry       Date:  2011-12-29       Impact factor: 3.162

Review 7.  Metabolism as a key to histone deacetylase inhibition.

Authors:  Praveen Rajendran; David E Williams; Emily Ho; Roderick H Dashwood
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-04-05       Impact factor: 8.250

8.  Life span extension and neuronal cell protection by Drosophila nicotinamidase.

Authors:  Vitaly Balan; Gregory S Miller; Ludmila Kaplun; Karina Balan; Zhao-Zhong Chong; Faqi Li; Alexander Kaplun; Mark F A VanBerkum; Robert Arking; D Carl Freeman; Kenneth Maiese; Guri Tzivion
Journal:  J Biol Chem       Date:  2008-08-04       Impact factor: 5.157

Review 9.  Decoding the epigenetic language of neuronal plasticity.

Authors:  Emiliana Borrelli; Eric J Nestler; C David Allis; Paolo Sassone-Corsi
Journal:  Neuron       Date:  2008-12-26       Impact factor: 17.173

Review 10.  Mechanisms and molecular probes of sirtuins.

Authors:  Brian C Smith; William C Hallows; John M Denu
Journal:  Chem Biol       Date:  2008-10-20
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