| Literature DB >> 17482404 |
Abstract
The level of telomerase activity is important in determining telomere length in aging cells and tissues. Here evidence on the importance of telomerase activity is reviewed with respect to aging rates of mammalian species and the health and life span of individuals within a species. The significance of telomerase reactivation for both cancer development and for immortalizing cells for therapeutic processes is assessed.Entities:
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Year: 2007 PMID: 17482404 PMCID: PMC1933587 DOI: 10.1016/j.exger.2007.03.007
Source DB: PubMed Journal: Exp Gerontol ISSN: 0531-5565 Impact factor: 4.032