Literature DB >> 17481965

From broken to old: DNA damage, IGF1 endocrine suppression and aging.

Raymond J Monnat1.   

Abstract

Two recent reports provide new information on how DNA damage may generate progeroid changes at the cell and organismal level by suppressing growth hormone (GH)/insulin-like growth factor 1 (IGF1) endocrine signaling. This endocrine signaling pathway is of particular interest as it is a key regulator of metabolism and longevity in many organisms.

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Year:  2007        PMID： 17481965      PMCID： PMC2704237          DOI： 10.1016/j.dnarep.2007.03.018

Source DB:  PubMed          Journal:  DNA Repair (Amst)        ISSN： 1568-7856


  16 in total

1.  Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

Authors:  M Ashburner; C A Ball; J A Blake; D Botstein; H Butler; J M Cherry; A P Davis; K Dolinski; S S Dwight; J T Eppig; M A Harris; D P Hill; L Issel-Tarver; A Kasarskis; S Lewis; J C Matese; J E Richardson; M Ringwald; G M Rubin; G Sherlock
Journal:  Nat Genet       Date:  2000-05       Impact factor: 38.330

2.  Extension of life-span with superoxide dismutase/catalase mimetics.

Authors:  S Melov; J Ravenscroft; S Malik; M S Gill; D W Walker; P E Clayton; D C Wallace; B Malfroy; S R Doctrow; G J Lithgow
Journal:  Science       Date:  2000-09-01       Impact factor: 47.728

3.  First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure.

Authors:  Nicolaas G J Jaspers; Anja Raams; Margherita Cirillo Silengo; Nils Wijgers; Laura J Niedernhofer; Andria Rasile Robinson; Giuseppina Giglia-Mari; Deborah Hoogstraten; Wim J Kleijer; Jan H J Hoeijmakers; Wim Vermeulen
Journal:  Am J Hum Genet       Date:  2007-01-29       Impact factor: 11.025

4.  Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence.

Authors:  G Weeda; I Donker; J de Wit; H Morreau; R Janssens; C J Vissers; A Nigg; H van Steeg; D Bootsma; J H Hoeijmakers
Journal:  Curr Biol       Date:  1997-06-01       Impact factor: 10.834

5.  Mice with DNA repair gene (ERCC-1) deficiency have elevated levels of p53, liver nuclear abnormalities and die before weaning.

Authors:  J McWhir; J Selfridge; D J Harrison; S Squires; D W Melton
Journal:  Nat Genet       Date:  1993-11       Impact factor: 38.330

Review 6.  A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan.

Authors:  Christy S Carter; Melinda M Ramsey; William E Sonntag
Journal:  Trends Genet       Date:  2002-06       Impact factor: 11.639

Review 7.  Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging.

Authors:  Andrzej Bartke
Journal:  Endocrinology       Date:  2005-05-26       Impact factor: 4.736

8.  ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

Authors:  Jochen G Schneider; Brian N Finck; Jie Ren; Kara N Standley; Masatoshi Takagi; Kirsteen H Maclean; Carlos Bernal-Mizrachi; Anthony J Muslin; Michael B Kastan; Clay F Semenkovich
Journal:  Cell Metab       Date:  2006-11       Impact factor: 27.287

9.  Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF.

Authors:  Ming Tian; Reiko Shinkura; Nobuhiko Shinkura; Frederick W Alt
Journal:  Mol Cell Biol       Date:  2004-02       Impact factor: 4.272

10.  Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

Authors:  Ingrid van der Pluijm; George A Garinis; Renata M C Brandt; Theo G M F Gorgels; Susan W Wijnhoven; Karin E M Diderich; Jan de Wit; James R Mitchell; Conny van Oostrom; Rudolf Beems; Laura J Niedernhofer; Susana Velasco; Errol C Friedberg; Kiyoji Tanaka; Harry van Steeg; Jan H J Hoeijmakers; Gijsbertus T J van der Horst
Journal:  PLoS Biol       Date:  2007-01       Impact factor: 8.029
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  7 in total

Review 1.  Chromatin regulation and genome maintenance by mammalian SIRT6.

Authors:  Ruth I Tennen; Katrin F Chua
Journal:  Trends Biochem Sci       Date:  2010-08-21       Impact factor: 13.807

Review 2.  Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology.

Authors:  Raymond J Monnat
Journal:  Semin Cancer Biol       Date:  2010-10-08       Impact factor: 15.707

3.  Characterization of CHO XPF mutant UV41: influence of XPF heterozygosity on double-strand break-induced intrachromosomal recombination.

Authors:  Leisa L Talbert; Luis Della Coletta; Megan G Lowery; Angela Bolt; David Trono; Gerald M Adair; Rodney S Nairn
Journal:  DNA Repair (Amst)       Date:  2008-06-10

Review 4.  How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?

Authors:  George Hinkal; Lawrence A Donehower
Journal:  Mech Ageing Dev       Date:  2008-02-17       Impact factor: 5.432

Review 5.  Genomic Approach to Understand the Association of DNA Repair with Longevity and Healthy Aging Using Genomic Databases of Oldest-Old Population.

Authors:  Yeo Jin Kim; Hyun Soo Kim; Young Rok Seo
Journal:  Oxid Med Cell Longev       Date:  2018-05-03       Impact factor: 6.543

Review 6.  GH and Senescence: A New Understanding of Adult GH Action.

Authors:  Vera Chesnokova; Shlomo Melmed
Journal:  J Endocr Soc       Date:  2021-11-22

Review 7.  DNA damage, cellular senescence and organismal ageing: causal or correlative?

Authors:  Jian-Hua Chen; C Nicholes Hales; Susan E Ozanne
Journal:  Nucleic Acids Res       Date:  2007-10-02       Impact factor: 16.971
  7 in total

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