Literature DB >> 17481745

Involvement of amygdaloid corticosterone in altered visceral and somatic sensation.

Brent Myers1, Kale Dittmeyer, Beverley Greenwood-Van Meerveld.   

Abstract

Behavioral responses to thermal and mechanical stimuli were used to examine somatic sensitivity in rats with stereotaxic corticosterone (CORT) implants on the amygdala. These animals have previously been shown to display anxiety-like behavior coupled with colonic hypersensitivity; in this study, CORT induced not only visceral hypersensitivity but also somatic hypersensitivity. These findings suggest that modulation of the amygdala with CORT results in a generalized decrease in sensory thresholds via descending neuronal pathways.

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Year:  2007        PMID： 17481745     DOI： 10.1016/j.bbr.2007.03.031

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN： 0166-4328            Impact factor:   3.332


  24 in total

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