| Literature DB >> 1748143 |
T Tsuchihashi1, A Tsukashima, K Matsumura, I Abe, M Tominaga, Y Nakao, K Kobayashi, M Fujishima.
Abstract
A newly developed calcium antagonist, nilvadipine, was administered to 7 hypertensive patients aged 75.6 y. Nilvadipine 4 mg b.d. decreased the average 24-h blood pressure significantly from 169/89 mmHg to 152/81 mmHg after 7 to 14 days without any change in the pulse rate. The circadian patterns of blood pressure and pulse rate were not affected by nilvadipine. Although the present study was a preliminary one done over a short period in a small number of patients, the results suggest that nilvadipine exerts an antihypertensive effect without altering the circadian pattern or the variability of blood pressure in elderly hypertensive patients.Entities:
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Year: 1991 PMID： 1748143 DOI： 10.1007/BF00315439
Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953