| Literature DB >> 17479299 |
Aoife Waters1, Valerie Langlois, Paul Thorner, Denis Geary.
Abstract
Postinfectious glomerulonephritis (PIGN) most commonly follows streptococcal infection. Antineutrophil cytoplasmic antibodies (ANCA) are characteristically negative in PIGN. We report on five cases who had positive atypical pANCA at presentation. The outcome was typical of other cases of PIGN with complete resolution of the glomerulonephritis in all five patients. Atypical pANCA occurs in a number of inflammatory conditions and antigenic targets may include proteins other than myeloperoxidase or proteinase 3. The presence of atypical p-ANCA does not indicate a poor prognosis.Entities:
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Year: 2007 PMID： 17479299 DOI： 10.1007/s00467-007-0495-1
Source DB: PubMed Journal: Pediatr Nephrol ISSN： 0931-041X Impact factor: 3.714