| Literature DB >> 17477912 |
Christina Loukou1, Manuela Tosin, Helge Müller-Bunz, Paul V Murphy.
Abstract
Sugar-lactams have found application as glycosidase inhibitors, synthetic precursors of iminosugars and they are structural components of natural products. The synthesis of beta-D-glucopyranosidurono-6,1-lactams from glucuronic acid derivatives are described. NMR data and X-ray crystal structures indicate that the sugar-lactams adopt distorted (1)C4 conformations in solution and in the solid state.Entities:
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Year: 2007 PMID： 17477912 DOI： 10.1016/j.carres.2007.04.003
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104