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Literature DB >> 17477911

Synthesis and biological evaluation of a small library of nojirimycin-derived bicyclic iminosugars.

Laura Cipolla¹, Marcos Reis Fernandes, Maria Gregori, Cristina Airoldi, Francesco Nicotra.

Abstract

Novel nojirimycin-derived bicyclic structures, containing cyclic carbamate, urea and guanidine moieties have been synthesised starting from suitably protected alpha-C-vinylnojirimycin and alpha-C-allylnojirimycin, respectively, and their biological activity against different glycosidases and as antibacterial agents tested.

Entities: Chemical

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Year: 2007 PMID： 17477911 DOI： 10.1016/j.carres.2007.04.002

Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104

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Cited

2 in total

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Authors: Paul Awolade; Nosipho Cele; Nagaraju Kerru; Lalitha Gummidi; Ebenezer Oluwakemi; Parvesh Singh
Journal: Eur J Med Chem Date: 2019-12-04 Impact factor: 6.514

2. Synthesis and biological evaluation of nojirimycin- and pyrrolidine-based trehalase inhibitors.

Authors: Davide Bini; Francesca Cardona; Matilde Forcella; Camilla Parmeggiani; Paolo Parenti; Francesco Nicotra; Laura Cipolla
Journal: Beilstein J Org Chem Date: 2012-04-05 Impact factor: 2.883

2 in total