| Literature DB >> 17477745 |
Eric Le Moal1, Emmanuel Fort, Sandrine Léve Que-Fort, Anne Janin, Hideyuki Murata, Fabrice P Cordelières, Marie-Pierre Fontaine-Aupart, Christian Ricolleau.
Abstract
Fluorescence microscopy has become the method of choice in the majority of life-science applications. We describe development and use of mirror slides to significantly enhance the fluorescence signal using standard air microscope objectives. This technique offers sufficient gain to achieve high-sensitivity imaging, together with wide field of observation and large depth of focus, two major breakthroughs for routine analysis and high-throughput screening applications on cells and tissue samples.Mesh：
Year: 2007 PMID： 17477745 DOI： 10.1117/1.2722730
Source DB: PubMed Journal: J Biomed Opt ISSN： 1083-3668 Impact factor: 3.170