Circulatory "efficacy" during progressive aerobic exercise in children: insights from the Q: VO(2) relationship.

The relationship between circulatory flow (Q) and oxygen uptake (VO2) may provide insights into performance of peripheral mechanisms which govern blood flow during exercise (circulatory efficacy). This study evaluated the response of Q relative to VO2 during progressive upright cycle exercise in a group of 39 preadolescent boys (mean age 12.2 +/- SD 0.5 years). The Q-VO2 relationship was curvilinear, best described by the cubic equation Q = 3.60(VO2)(3) + 5.24(VO2)(2) + 2.40(VO2) - 0.94. Circulatory efficacy, defined as the %DeltaQ/%DeltaVO2 x 100, fell from 70.4% between the first two workloads to 49.7% at peak exercise. This decline in circulatory efficacy is consistent with other published data suggesting a decline in skeletal muscle pump function at high intensity workloads. The pattern of change in relationship of Q and VO2 during progressive exercise in these children is similar to that observed in studies of adults. This implies that performance of peripheral determinants of circulatory responses to exercise is not affected by biological maturation.