Literature DB >> 17476051

ImmunoGrid - the virtual human immune system project.

Andrew Emerson1, Elda Rossi.   

Abstract

ImmunoGrid is a 3 year project funded by the European Union which began in February 2006 and establishes an infrastructure for the simulation of the immune system that integrates processes at molecular, cellular and organ levels. It is designed for applications that support clinical outcomes such as the design of vaccines, immunotherapies and optimization of immunization protocols. The first phase of the project concentrated on improving and extending current models of the immune system. We are now entering the second phase which will design and implement a human immune system simulator. Since the new models are orders of magnitude more complex than the previous ones, grid technologies will be essential in providing the necessary computer infrastructure. The final phase of the project will validate the simulator with pre-clinical trials using mouse models.

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Year:  2007        PMID: 17476051

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN: 0926-9630


  4 in total

Review 1.  Accessing and integrating data and knowledge for biomedical research.

Authors:  A Burgun; O Bodenreider
Journal:  Yearb Med Inform       Date:  2008

2.  ENteric Immunity SImulator: a tool for in silico study of gastroenteric infections.

Authors:  Katherine V Wendelsdorf; Maksudul Alam; Josep Bassaganya-Riera; Keith Bisset; Stephen Eubank; Raquel Hontecillas; Stefan Hoops; Madhav Marathe
Journal:  IEEE Trans Nanobioscience       Date:  2012-09       Impact factor: 2.935

Review 3.  Review of the systems biology of the immune system using agent-based models.

Authors:  Snehal B Shinde; Manish P Kurhekar
Journal:  IET Syst Biol       Date:  2018-06       Impact factor: 1.615

4.  Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment.

Authors:  Kerri-Ann Norton; Chang Gong; Samira Jamalian; Aleksander S Popel
Journal:  Processes (Basel)       Date:  2019-01-13       Impact factor: 2.847

  4 in total

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