| Literature DB >> 17475345 |
Timothy South1, Chao Deng, Xu-Feng Huang.
Abstract
This experiment aimed to examine the role of the CB1 and Opioid mu receptors on fat preference by administering the CB1 inverse agonist AM 251 (5mg/kg i.p.) and the opioid mu antagonist beta-Funaltrexamine (15mg/kg s.c.) for 4 days to fat-preferring C57BL/6 mice fed a two-choice high-fat/low-fat diet. Both drugs were found to significantly reduce total energy intake, high-fat diet intake and fat preference during treatment.Entities:
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Year: 2007 PMID： 17475345 DOI： 10.1016/j.bbr.2007.03.028
Source DB: PubMed Journal: Behav Brain Res ISSN： 0166-4328 Impact factor: 3.332