EDTA-dependent lymphoagglutination in a patient with non-Hodgkin lymphoma.

Lymphoagglutination is a rare EDTA-dependent phenomenon far less frequent than neutrophil agglutination. It usually involves normal lymphocytes, but has also been reported in lymphoproliferative disorders. We report the case of a woman who developed artifactual agglutination of both normal and lymphoma cells in the context of an unusual primary cutaneous leg type B-cell non-Hodgkin's malignancy, raising the potential of misdiagnosis.