| Literature DB >> 17474779 |
Giuseppe Borsato1, Anthony Linden, Ottorino De Lucchi, Vittorio Lucchini, David Wolstenholme, Alfonso Zambon.
Abstract
3-Chloronorbornenone (R)-1a (98% ee) was obtained from trichloronorbornene 5 in two steps by the in situ generation of dichloronorbornadiene 2a with t-BuOK and desymmetrization with (-)-ephedrine, followed by hydrolysis with PPTS. The generality of this desymmetrization with (-)-ephedrine was tested with dibromonorbornadiene 2c and other substituted dichloronorbornadienes.Entities:
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Year: 2007 PMID： 17474779 DOI： 10.1021/jo070222g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354