Literature DB >> 17474516

Microbiological assay for cefoxitin sodium in dosage form.

Hérida Regina Nunes Salgado1, Greici Cristiani Gomes Tozo.   

Abstract

A microbiological assay applying the cylinder-plate method is described for determination of the activity of cefoxitin sodium in injectables. Using a strain of Staphylococcus epidermidis ATCC 12226 as the test organism, cefoxitin sodium was measured in concentrations ranging from 50.0 to 200.0 microg/mL. The validation showed that the method was linear (r = 0.9998), precise (RSD = 0.81%), and accurate. It was concluded that the microbiological assay is satisfactory for quantitation of cefoxitin sodium in injectables.

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Year:  2007        PMID： 17474516

Source DB:  PubMed          Journal:  J AOAC Int        ISSN： 1060-3271            Impact factor:   1.913


  4 in total

1.  Development and validation of a microbiological agar assay for determination of orbifloxacin in pharmaceutical preparations.

Authors:  Edith C L Cazedey; Hérida R N Salgado
Journal:  Pharmaceutics       Date:  2011-08-29       Impact factor: 6.321

Review 2.  Selection of appropriate analytical tools to determine the potency and bioactivity of antibiotics and antibiotic resistance.

Authors:  Nishant A Dafale; Uttam P Semwal; Rupak K Rajput; G N Singh
Journal:  J Pharm Anal       Date:  2016-05-24

3.  Application of microbiological assay to determine pharmaceutical equivalence of generic intravenous antibiotics.

Authors:  Andres F Zuluaga; Maria Agudelo; Carlos A Rodriguez; Omar Vesga
Journal:  BMC Clin Pharmacol       Date:  2009-01-16

4.  Development and validation of a successful microbiological agar assay for determination of ceftriaxone sodium in powder for injectable solution.

Authors:  Patrícia V Aléssio; Hérida R N Salgado
Journal:  Pharmaceutics       Date:  2012-06-29       Impact factor: 6.321
  4 in total

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