Literature DB >> 1747308

Acceleration of wound healing by local application of fibronectin.

G Scheel1, B Rahfoth, J Franke, P Grau.   

Abstract

The process of wound healing under the influence of locally applied fibronectin, heparin and thrombin was studied in adult rabbits. Using immunofluorescence microscopy, a higher concentration of fibronectin within the wound area was found on the 1st day after fibronectin treatment. The tensile strength of the wounds was tested on the 6th, 9th and 12th day after operation. On the 9th day the tensile strength of the fibronectin-treated wounds was significantly higher than that of the control wounds on the 12th day after operation. The addition of heparin and thrombin, each in combination with fibronectin, did not show any significant effect on wound healing.

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Year:  1991        PMID： 1747308     DOI： 10.1007/bf00443459

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN： 0936-8051            Impact factor:   3.067


  19 in total

1.  Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors.

Authors:  R Pytela; M D Pierschbacher; M H Ginsberg; E F Plow; E Ruoslahti
Journal:  Science       Date:  1986-03-28       Impact factor: 47.728

2.  The effect of exogenous fibronectin on wound breaking strength.

Authors:  P A Falcone; M Bonaventura; D C Turner; D Fromm
Journal:  Plast Reconstr Surg       Date:  1984-12       Impact factor: 4.730

3.  Distribution of fibronectin on peripheral blood cells in freshly clotted blood.

Authors:  F Grinnell; M K Feld
Journal:  Thromb Res       Date:  1981 Dec 1-15       Impact factor: 3.944

4.  Role of attachment factors and attractants in fibroblast chemotaxis.

Authors:  V Gauss-Müller; H K Kleinman; G R Martin; E Schiffmann
Journal:  J Lab Clin Med       Date:  1980-12

5.  Purification of fibronectin from human plasma by affinity chromatography under non-denaturing conditions.

Authors:  M Vuento; A Vaheri
Journal:  Biochem J       Date:  1979-11-01       Impact factor: 3.857

6.  The influence of fixation and tissue preparation on the immunohistochemical demonstration of fibronectin in human tissue.

Authors:  B Hølund; P P Clausen; I Clemmensen
Journal:  Histochemistry       Date:  1981

7.  Heparin enhances the rate of binding of fibronectin to collagen.

Authors:  S Johansson; M Höök
Journal:  Biochem J       Date:  1980-05-01       Impact factor: 3.857

8.  Heparin binding is necessary, but not sufficient, for fibronectin aggregation. A fluorescence polarization study.

Authors:  K L Bentley; R J Klebe; R E Hurst; P M Horowitz
Journal:  J Biol Chem       Date:  1985-06-25       Impact factor: 5.157

9.  Factor XIII cross-linking of fibronectin at cellular matrix assembly sites.

Authors:  E L Barry; D F Mosher
Journal:  J Biol Chem       Date:  1988-07-25       Impact factor: 5.157

10.  Influence of factor XIII and fibronectin on fiber size and density in thrombin-induced fibrin gels.

Authors:  M E Carr; D A Gabriel; J McDonagh
Journal:  J Lab Clin Med       Date:  1987-12
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  3 in total

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Authors:  S S AbiEzzi; R A Foulk; F L Harwood; W H Akeson; D Amiel
Journal:  Iowa Orthop J       Date:  1997

2.  Development of the biologically active Guglielmi detachable coil for the treatment of cerebral aneurysms. Part II: an experimental study in a swine aneurysm model.

Authors:  Y Murayama; F Viñuela; Y Suzuki; Y Akiba; A Ulihoa; G R Duckwiler; Y P Gobin; H V Vinters; M Iwaki; T Abe
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3.  A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p.

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  3 in total

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