BACKGROUND: Amyotrophic lateral sclerosis, Parkinson's disease, atypical parkinsonian syndromes, and multiple sclerosis are progressive neurologic disorders that cumulatively afflict a large number of people. Effective end-of-life palliative care depends upon an understanding of the clinical aspects of each of these disorders. OBJECTIVES: The authors review the unique and overlapping aspects of each of these disorders with an emphasis upon the clinical management of symptoms. DESIGN: The authors review current management and the supporting literature. CONCLUSIONS: Clinicians have many effective therapeutic options to choose from when managing the symptoms produced by these disorders.
BACKGROUND:Amyotrophic lateral sclerosis, Parkinson's disease, atypical parkinsonian syndromes, and multiple sclerosis are progressive neurologic disorders that cumulatively afflict a large number of people. Effective end-of-life palliative care depends upon an understanding of the clinical aspects of each of these disorders. OBJECTIVES: The authors review the unique and overlapping aspects of each of these disorders with an emphasis upon the clinical management of symptoms. DESIGN: The authors review current management and the supporting literature. CONCLUSIONS: Clinicians have many effective therapeutic options to choose from when managing the symptoms produced by these disorders.
Authors: Surya K Mallapragada; Timothy M Brenza; JoEllyn M McMillan; Balaji Narasimhan; Donald S Sakaguchi; Anup D Sharma; Svitlana Zbarska; Howard E Gendelman Journal: Nanomedicine Date: 2015-01-31 Impact factor: 5.307
Authors: Kelly Fahrner-Scott; Carly Zapata; David L O'Riordan; Eve Cohen; Laura Rosow; Steven Z Pantilat; Catherine Lomen-Hoerth; Kara E Bischoff Journal: Neurol Clin Pract Date: 2022-02
Authors: Katrien Moens; Dirk Houttekier; Lieve Van den Block; Richard Harding; Lucas Morin; Stefano Marchetti; Agnes Csikos; Martin Loucka; Wayne A Naylor; Donna M Wilson; Joan Teno; Marylou Cardenas-Turanzas; YongJoo Rhee; Francisco Javier Garcia-Leon; Luc Deliens; Joachim Cohen Journal: BMC Palliat Care Date: 2015-05-20 Impact factor: 3.234