Literature DB >> 1747233

Intrathecal narcotics for relief of pain from head and neck cancer.

P E Andersen1, J I Cohen, E C Everts, M D Bedder, K J Burchiel.   

Abstract

We describe our experience with nine patients with head and neck pain of malignant origin who were treated with continuous low-dose intrathecal morphine via a lumbar catheter and implantable subcutaneous drug delivery pump. All patients had failed prior attempts at oral narcotic pain control due to either poor pain control or intolerable side effects. Using a visual analogue scale where the most severe pain is rated as 10 and no pain is rated as 0, the mean visual analogue scale was reduced from 7.6/10 (range, 5 to 10/10) before implantation to 1.9/10, 2.0/10, and 0.5/10 at 1 week, 1 month, and 2 months after implantation, respectively. Complications were acceptable. We conclude that intrathecal administration of morphine is a safe and effective means of pain control. This method deserves serious consideration in patients with intractable pain secondary to head and neck malignancy.

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Year:  1991        PMID: 1747233     DOI: 10.1001/archotol.1991.01870230093015

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  1 in total

1.  High Cervical Intrathecal Targeted Drug Delivery: A Case Report of Refractory Oropharyngeal Cancer Pain.

Authors:  Rajat N Moman; Julie M Rogers; Thomas P Pittelkow
Journal:  Case Rep Oncol Med       Date:  2019-09-10
  1 in total

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